KIAA1683蛋白抗体

产品货号 :  jlcR17021
英文名称 :  KIAA1683
中文名称 :  KIAA1683蛋白抗体
别    名 :  K1683_HUMAN; KIAA1683; Uncharacterized protein KIAA1683.  
研究领域 :  细胞生物  表观遗传学  
抗体来源 :  Rabbit
克隆类型 :  Polyclonal
交叉反应 :  Human,
产品应用 :  ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 :  128kDa
细胞定位 :  细胞核 细胞浆
性    状 :  Lyophilized or Liquid
浓    度 :  1mg/ml
免 疫 原 :  KLH conjugated synthetic peptide derived from human KIAA1683:551-650/1180
亚    型 :  IgG
纯化方法 :  affinity purified by Protein A
储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed :  PubMed
产品介绍 :   KIAA1683 is a 1,180 amino acid protein that contains six IQ domains, exists as three alternatively spliced isoforms, and is encoded by a gene that maps to human chromosome 19p13.11. Consisting of around 63 million bases with over 1,400 genes, chromosome 19 makes up over 2% of human genomic DNA. Chromosome 19 includes a diversity of interesting genes and is recognized for having the greatest gene density of the human chromosomes. It is the genetic home for a number of immunoglobulin superfamily members including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG families, and Fcα receptors. Key genes for eye color and hair color also map to chromosome 19. Peutz-Jeghers syndrome, spinocerebellar ataxia type 6, the stroke disorder CADASIL, hypercholesterolemia and insulin-dependent diabetes have been linked to chromosome 19. Translocations with chromosome 19 and chromosome 14 can be seen in some lymphoproliferative disorders and typically involve the proto-oncogene BCL3.

Post-translational modifications:
Phosphorylated upon DNA damage, probably by ATM or ATR.

DISEASE:
Contains 6 IQ domains.

Similarity:
Contains 6 IQ domains.

SWISS:
Q9H0B3

Gene ID:
80726

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.