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- 详细信息
- 技术资料
- 供应商:
江西江蓝纯生物试剂有限公司
- 库存:
大量
- 克隆性:
多克隆
- 保质期:
1年
- 抗体英文名:
Anti-ITM2B antibody
- 宿主:
Rabbit
- 浓度:
1.2 mg/ml
- 保存条件:
-20°C
- 规格:
25 μl/100 μl/200 μl

Anti-ITM2B antibody
Cat. No. JLC224809
Package 25 μl/100 μl/200 μl
Storage -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Product overview
Description Anti-ITM2B rabbit polyclonal antibody
Applications ELISA, WB, IHC
Immunogen Fusion protein of human ITM2B
Reactivity Human, Mouse, Rat
Content 1.2 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol ITM2B
Full name integral membrane protein 2B
Synonyms BRI; FBD; ABRI; BRI2; E25B; E3-16; RDGCA; imBRI2; BRICD2B
Swissprot Q9Y287
Target Background
Amyloid precursor proteins are processed by beta-secretase and gamma-secretase to produce beta-amyloid peptides which form the characteristic plaques of Alzheimer disease. This gene encodes a transmembrane protein which is processed at the C-terminus by furin or furin-like proteases to produce a small secreted peptide which inhibits the deposition of beta-amyloid. Mutations which result in extension of the C-terminal end of the encoded protein, thereby increasing the size of the secreted peptide, are associated with two neurogenerative diseases, familial British dementia and familial Danish dementia.
Applications
Immunohistochemistry
Predicted cell location: Cytoplasm
Positive control: Human liver cancer
Recommended dilution: 30-150
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using ml224809(ITM2B Antibody) at dilution 1/35, on the right is treated with fusion protein. (Original magnification: ×200)
Western blotting
Predicted band size:30 kDa
Positive control:Rat kidney tissue lysate
Recommended dilution: 500-2000
Gel: 12%SDS-PAGE
Lysate: 40 μg
Lane: Rat kidney tissue lysate
Primary antibody: ml224809(ITM2B Antibody) at dilution 1/500
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution
Exposure time: 30 seconds
ELISA
Recommended dilution: 5000-10000
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Anti-ITM2B antibody
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