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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
A synthetic phosphorylated peptide around T180 & Y182 of human p38 MAPK
- 亚型:
IgG
- 形态:
liquid
- 保存条件:
负20摄氏度
- 克隆性:
polyclonal
- 标记物:
Non-conjugated
- 适应物种:
Human
- 保质期:
6个月
- 抗原来源:
Rabbit
- 目录编号:
Q9BZJ3
- 级别:
纯化级别
- 库存:
50
- 供应商:
LSM bio
- 宿主:
E. coli - derived recombinant protein
- 应用范围:
ELISA, WB
- 浓度:
≥95% as determined by SDS-PAGE
- 靶点:
A synthetic phosphorylated peptide around T180 & Y182 of human p38 MAPK
- 抗体英文名:
Phospho- MAPK14(T180/Y182) antibody
- 抗体名:
Phospho- MAPK14(T180/Y182) antibody
- 规格:
100μl
Phospho- MAPK14(T180/Y182) antibody
Product Name Phospho- MAPK14(T180/Y182) antibody
Catalog No PAab10117
Packing 100ul
Form liquid
Alternative Name CSBP, CSBP1, CSBP2, CSPB1, EXIP, Mxi2, PRKM14, PRKM15, RK, SAPK2A, p38, p38ALPHA
Purification Immunogen affinity purified
Purity 95% as determined by SDS-PAGE
Host Rabbit
Isotype IgG
Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)
Background/ FUNCTION
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Immunogen A synthetic phosphorylated peptide around T180 & Y182 of human p38 MAPK
Specificity Human
Tested Application ELISA, WB
Recommended dilution WB: 1:500-1:2000
IHC use
WB use
Hela cells were subjected to SDS PAGE followed by western blot with PAab10117 at dilution of 1:1000
Protein Information
Gene ID 1432
Uniprot ID Q16539
Calculated MW 41kDa
Research Area Cancer, Immunology, Signal Transduction, epigenetics
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