- ￥2260
- LSM Bio
- 进口
- PAab10089
- 2025年07月09日
- ELISA, IHC
- E. coli - derived recombinant protein
- Human, Mouse, Rat
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
CD44 molecule
- 亚型：
IgG
- 形态：
liquid
- 保存条件：
负20摄氏度
- 克隆性：
polyclonal
- 标记物：
Non-conjugated
- 适应物种：
Human, Mouse, Rat
- 保质期：
6个月
- 抗原来源：
Rabbit
- 目录编号：
Q9BZJ3
- 级别：
纯化级别
- 库存：
50
- 供应商：
LSM bio
- 宿主：
E. coli - derived recombinant protein
- 应用范围：
ELISA, IHC
- 浓度：
≥95% as determined by SDS-PAGE
- 靶点：
CD44 molecule
- 抗体英文名：
CD44 antibody
- 抗体名：
CD44 antibody
- 规格：
100μl
CD44 antibody
Product Name CD44 antibody
Catalog No PAab10089
Packing 100ul
Form liquid
Alternative Name LHR, MDU2, MDU3, MIC4
Purification Immunogen affinity purified
Purity 95% as determined by SDS-PAGE
Host Rabbit
Isotype IgG
Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)
Background/ FUNCTION
The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis.
Immunogen CD44 molecule
Specificity Human, Mouse, Rat
Tested Application ELISA, IHC
Recommended dilution IHC: 1:20-1:200
IHC use Immunohistochemistry of paraffin-embedded rat spleen tissue slide using PAab10089( CD44 Antibody) at dilution of 1:200
WB use
Protein Information
Gene ID 960
Uniprot ID P16070
Calculated MW 79 kDa
Research Area Stem Cells, Immunology, Cardiovascular, Cancer
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文献和实验CD44/CD44R 分子 CD44 常用单克隆抗体或代号： GRHL1,Hermes,F10- 44- 2(Pgp- 1H- CAM,ECM- RⅢ) 主要表达细胞： Leu,上皮,Fb,RBC[AS] 分子质量(kDa)和结构： gp80- 95 功 能： 粘附ECM,T细胞活化,淋巴细胞归位受体,归位到HEV CD44R 常用单克隆抗体或代号： FM11,24
对CD44的研究时间较长、较深入亦较广泛。已知其为分布极为广泛的细胞表面跨膜糖蛋白，主要参与异质性粘附，即肿瘤细胞与宿主细胞和宿主基质的粘附，异质性粘附在肿瘤细胞侵袭转移中起促进作用。 人类CD44基因位于11号染色体短臂，全长约50kb，共由20个高度保守的外显子组成，每个外显子长度70-210bp不等，中间由长短不一的内含子分隔。CD44基因的20个外显子按照转录方式不同可分为组成型外显子（C）和变异型拼接外显子（V）两大类。组成型外显子共有10个，存在
PCR Analysis of CD44 Variants in Tumors
The CD44 molecule is a transmembrane glycoprotein, it is an acidic, sul fated protein that contains multiple phosphoserine residues and several intrachain disulfide bonds. It is essentially composed of a 37-kDa protein core highly glycosylated
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