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- 详细信息
- 文献和实验
- 技术资料
- 供应商:
江西江蓝纯生物试剂有限公司
- 库存:
75
- 克隆性:
单克隆
- 保质期:
1年
- 抗体英文名:
human CD3-APC
- 抗体名:
APC标记小鼠抗人CD3单克隆抗体
- 适应物种:
人/动物/植物
- 应用范围:
WB,ELISA等
- 浓度:
1mg/ml
- 保存条件:
-20 °
- 规格:
25T/100T
| 规格: | 25T | 产品价格: | ¥440.0 |
|---|---|---|---|
| 规格: | 100T | 产品价格: | ¥1000.0 |
英文名称 : human CD3-APC
中文名称 : APC标记小鼠抗人CD3单克隆抗体
别 名 : CD3 epsilon; CD3e; CD3e antigen epsilon polypeptide (TiT3 complex); CD3E antigen epsilon polypeptide; CD3E antigen, epsilon subunit; CD3e molecule epsilon; CD3e molecule, epsilon (CD3 TCR complex); CD3e molecule, epsilon (CD3-TCR complex); CD3E_HUMAN; IMD18; T cell antigen receptor complex epsilon subunit of T3; T cell surface antigen T3/Leu 4 epsilon chain; T cell surface glycoprotein CD3 epsilon chain; T-cell surface antigen T3/Leu-4 epsilon chain; T-cell surface glycoprotein CD3 epsilon chain; T3E; TCRE.
抗体来源 : Mouse
克隆类型 : Monoclonal
克 隆 号 : HIT3a
交叉反应 : Human,
产品应用 : Flow-Cyt=20μl/Test
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 : 20kDa
细胞定位 : 细胞膜
性 状 : Liquid
亚 型 : IgG2a
纯化方法 : affinity purified by Protein G
储 存 液 : 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 : Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed : PubMed
产品介绍 : The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008].
Function:
The CD3 complex mediates signal transduction.
Subunit:
The TCR/CD3 complex of T-lymphocytes consists of either a TCR alpha/beta or TCR gamma/delta heterodimer coexpressed at the cell surface with the invariant subunits of CD3 labeled gamma, delta, epsilon, zeta, and eta.
Subcellular Location:
Membrane; Single-pass type I membrane protein.
Similarity:
Contains 1 Ig-like (immunoglobulin-like) domain.
Contains 1 ITAM domain.
SWISS:
P07766
Gene ID:
916
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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