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- 人/动物/植物
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- 详细信息
- 文献和实验
- 技术资料
- 供应商：
江西江蓝纯生物试剂有限公司
- 库存：
160
- 克隆性：
单克隆
- 保质期：
1年
- 抗体英文名：
CXCL4
- 抗体名：
血小板因子4抗体
- 适应物种：
人/动物/植物
- 应用范围：
WB,ELISA等
- 浓度：
1mg/ml
- 保存条件：
-20 °
- 规格：
50ul/100ul/200ul
| 规格： | 50ul | 产品价格： | ¥880.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ¥1580.0 |
| 规格： | 200ul | 产品价格： | ¥2480.0 |
英文名称 : CXCL4
中文名称 : 血小板因子4抗体
别 名 : C-X-C motif chemokine 4; Chemokine (C X C motif) ligand 4; Chemokine (CXC motif) ligand 4; CXCL 4; CXCL4; Iroplact; MGC138298; Oncostatin A; Oncostatin-A; OncostatinA; PF 4; PF-4; PF4; Platelet factor 4; PLF4_HUMAN; SCYB 4; SCYB4; short form; Small inducible cytokine subfamily member 4.
研究领域 : 细胞生物 免疫学 生长因子和激素 趋化因子 血管内皮细胞
抗体来源 : Rabbit
克隆类型 : Polyclonal
交叉反应 : Human, Mouse, Rat, Cow, Rabbit,
产品应用 : WB=1:500-2000 ELISA=1:500-1000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 : 11kDa
细胞定位 : 分泌型蛋白
性 状 : Lyophilized or Liquid
浓 度 : 1mg/ml
免 疫 原 : KLH conjugated synthetic peptide derived from human CXCL:32-101/101
亚 型 : IgG
纯化方法 : affinity purified by Protein A
储 存 液 : 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 : Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed : PubMed
产品介绍 : Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7 transmembrane, G protein coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC, based on the arrangement of the first 2 of the 4 conserved cysteine residues; the 2 cysteines are separated by a single amino acid in CXC chemokines and are adjacent in CC chemokines. CXC chemokines are further subdivided into ELR and non ELR types based on the presence or absence of a glu leu arg sequence adjacent and N terminal to the CXC motif.
Function:
Released during platelet aggregation. Neutralizes the anticoagulant effect of heparin because it binds more strongly to heparin than to the chondroitin-4-sulfate chains of the carrier molecule. Chemotactic for neutrophils and monocytes. Inhibits endothelial cell proliferation, the short form is a more potent inhibitor than the longer form.
Subunit:
Homotetramer.
Subcellular Location:
Secreted.
Similarity:
Belongs to the intercrine alpha (chemokine CxC) family.
SWISS:
P02776
Gene ID:
5196
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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文献和实验血小板抗体的概述是检验主管技师考试要求掌握的内容，医学教育网搜集整理相关内容供大家参考。 同种抗体：由输血或妊娠等同种免疫产生，多为IgG型。自身抗体：多在原发性血小板减少性紫癜中检出，也多为IgG型。
血小板因子Ⅲ（PF3）有效性测定 【参考范围】被检者血浆与正常富含血小板血浆（PRP）及乏血小板血浆（PPP）分别反应，后者较前者凝血时间（检测器法）延长不超过5s.【影响因素】1.最好采用硅化或塑料注射器，玻璃试管等需涂硅处理或使用塑料制品。因为玻璃可以激活凝血反应。 2.较理想的抗凝剂应首选枸橼酸钠。 3.止血带不应扎得太紧，时间最好不超过5min，医学教|育网搜集整理并强调采血顺利，以防激活凝血反应。 4.PF3有效测定的准确性取决于富含血小板
血小板相关抗体 【参考范围】1.PAIgG0～78.8ng/10^7PLT（放免法）。 2.PAIgA0～2ng/10^7PLT（放免法）。 3.PAIgM0～7ng/10^7PLT（放免法）。 4.PAC330～129ng/10^7PLT（放免法）。 【影响因素】1.最好采用硅化或塑料注射器医学教|育网搜集整理，玻璃试管等需涂硅处理或使用塑料制品。因为玻璃可以激活凝血反应。 2.因肾上腺皮质激素可影响结果，故应停药2周以上才能抽血
