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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
UPF3 regulator of nonsense transcripts homolog B (yeast)
- 亚型:
IgG
- 形态:
liquid
- 保存条件:
负20摄氏度
- 克隆性:
Polyclonal antibody
- 标记物:
Non-conjugated
- 适应物种:
Human,Mouse ,Rat
- 保质期:
6个月
- 抗原来源:
Rabbit
- 目录编号:
Q9BZJ3
- 级别:
纯化级别
- 库存:
50
- 供应商:
LSM bio
- 宿主:
E. coli - derived recombinant protein
- 应用范围:
ELISA,WB,IHC
- 浓度:
≥95% as determined by SDS-PAGE
- 靶点:
UPF3 regulator of nonsense transcripts homolog B (yeast)
- 抗体英文名:
anti-UPF3B antibody,UPF3B antibody
- 抗体名:
anti-UPF3B 抗体,UPF3B 抗体
- 规格:
100μl
UPF3B抗体| UPF3B antibody
货号 PAab09272
蛋白别名 HUPF3B antibody, hUpf3p X antibody, MRXS14 antibody, RENT3B antibody, UPF3B antibody, UPF3X
蛋白介绍
Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons by associating with the nuclear exon junction complex (EJC) and serving as link between the EJC core and NMD machinery. Recruits UPF2 at the cytoplasmic side of the nuclear envelope and the subsequent formation of an UPF1-UPF2- UPF3 surveillance complex (including UPF1 bound to release factors at the stalled ribosome) is believed to activate NMD. In cooperation with UPF2 stimulates both ATPase and RNA helicase activities of UPF1. Binds spliced mRNA upstream of exon-exon junctions. In vitro, stimulates translation; the function is independent of association with UPF2 and components of the EJC core.
产品描述
anti-UPF3B antibody is a Rabbit Polyclonal antibody againstUPF3B..
建议稀释比例
WB : 1:500-1:5000;IHC:1:20-1:200
IHC
Immunohistochemistry of paraffin-embedded human testis slide using PAab09272( UPF3B Antibody) at dilution of 1:50
Western blot
Jurkat cells were subjected to SDS PAGE followed by western blot with PAab09272(UPF3B antibody) at dilution of 1:2000(本抗体仅供体外科研用途,不可用于临床诊断!) "">
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