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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
alkB, alkylation repair homolog 7 (E. coli)
- 亚型:
IgG
- 形态:
liquid
- 保存条件:
负20摄氏度
- 克隆性:
Polyclonal antibody
- 标记物:
Non-conjugated
- 适应物种:
Human,Mouse ,Rat
- 保质期:
6个月
- 抗原来源:
Rabbit
- 目录编号:
Q9GZT9
- 级别:
纯化级别
- 库存:
50
- 供应商:
LSM bio
- 宿主:
E. coli - derived recombinant protein
- 应用范围:
ELISA,WB,IHC
- 浓度:
≥95% as determined by SDS-PAGE
- 靶点:
ALKBH7
- 抗体英文名:
anti-ALKBH7 antibody,ALKBH7 antibody
- 抗体名:
anti-ALKBH7 抗体,ALKBH7 抗体
- 规格:
100μg
ALKBH7抗体| ALKBH7 antibody
货号 PAab00315
蛋白别名 ABH7 antibody, ALKBH7 antibody, SPATA11 antibody, UNQ6002
蛋白介绍
May function as protein hydroxylase; can catalyze auto- hydroxylation at Leu-110 (in vitro), but this activity may be due to the absence of the true substrate (PubMed:25122757). Required to induce programmed necrosis in response to DNA damage caused by cytotoxic alkylating agents. Acts by triggering the collapse of mitochondrial membrane potential and loss of mitochondrial function that leads to energy depletion and cell death (PubMed:23666923). ALKBH7-mediated necrosis is probably required to prevent the accumulation of cells with DNA damage (PubMed:23666923). Does not display DNA demethylase activity (PubMed:23666923). Involved in fatty acid metabolism (By similarity).
产品描述
anti-ALKBH7 antibody is a Rabbit Polyclonal antibody againstALKBH7..
建议稀释比例
WB :1:200-1:2000;IHC:1:20-1:200
IHC
Immunohistochemistry of paraffin-embedded human testis tissue slide using PAab00315( ALKBH7 Antibody) at dilution of 1:50
Western blot
human testis tissue were subjected to SDS PAGE followed by western blot with PAab00315(ALKBH7 antibody) at dilution of 1:500(本抗体仅供体外科研用途,不可用于临床诊断!)
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文献和实验
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