- ￥2260
- LSM Bio
- 进口
- PAab09393
- 2025年07月13日
- ELISA,WB,IP,IF
- E. coli - derived recombinant protein
- Human,Mouse ,Rat
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)
- 亚型：
IgG
- 形态：
liquid
- 保存条件：
负20摄氏度
- 克隆性：
Polyclonal antibody
- 标记物：
Non-conjugated
- 适应物种：
Human,Mouse ,Rat
- 保质期：
6个月
- 抗原来源：
Rabbit
- 目录编号：
Q9BZJ3
- 级别：
纯化级别
- 库存：
50
- 供应商：
LSM bio
- 宿主：
E. coli - derived recombinant protein
- 应用范围：
ELISA,WB,IP,IF
- 浓度：
≥95% as determined by SDS-PAGE
- 靶点：
fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)
- 抗体英文名：
anti-VEGFR-1/FLT-1 antibody,VEGFR-1/FLT-1 antibody
- 抗体名：
anti-VEGFR-1/FLT-1 抗体,VEGFR-1/FLT-1 抗体
- 规格：
100μl
VEGFR-1/FLT-1抗体| VEGFR-1/FLT-1 antibody
货号 PAab09393
蛋白别名 FLT antibody, FLT 1 antibody, FLT1 antibody, FLT-1 antibody, Fms like tyrosine kinase 1 antibody, FRT antibody, sflt1 antibody, Tyrosine protein kinase FRT antibody, VEGF receptor 1 antibody, VEGFR 1 antibody, VEGFR1 antibody, VEGFR-1
蛋白介绍
Vascular endothelial growth factor receptor-1 (VEGFR-1, FLT-1) is a receptor tyrosine kinase belonging to the VEGFR family. VEGF is a key regulator of physiological angiogenesis and has also been implicated in pathological angiogenesis associated with tumors, intraocular neovascular disorders and other conditions. The biological effects of VEGF are mediated by VEGFR-1 and VEGFR-2. Both the two receptors have seven immunoglobulin-like repeats in the extracellular domain, a single transmembrane region and a tyrosine kinase domain. VEGFR-1 binds VEGFA, PIGF and VEGFB, and plays an essential role in the development of embryonic vasculature, the regulation of angiogenesis, cell survival, cell migration, macrophage function, chemotaxis, and cancer cell invasion. Two isoforms of VEGFR-1 exist, a full-length transmembrane form and a short souble form (sVEGFR-1) consisting of only the extracellular ligand-binding domain. (PMID: 12778165; 17109193; 8806634)
产品描述
anti-VEGFR-1/FLT-1 antibody is a Rabbit Polyclonal antibody againstVEGFR-1/FLT-1..
建议稀释比例
WB :1:200-1:2000;IP:1:200-1:2000;IF:1:10-1:100
IHC
Western blot
HEK-293 cells were subjected to SDS PAGE followed by western blot with PAab09393(VEGFR1, FLT1 antibody) at dilution of 1:800(本抗体仅供体外科研用途，不可用于临床诊断!) "">
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文献和实验dscgu 迄今已发现了VEGF的三种酪氨酸蛋白激酶受体，分别是VEGFR-1（flt-1）、VEGFR-2（flk-1，也称KDR）、VEGFR-3（flt-4）。 是否能选择性抑制VEGFR-1（flt-1）、VEGFR-2（flk-1，也称KDR）、 freecell ZM323881, a VEGF receptor (Flk-1)-specific inhibitor http://www.ncbi
生长因子）。而VEGFR也分成1、2、3三种，在血管内皮细胞，造血干细胞，单核细胞和巨噬细胞上表达的是VEGFR1（Flt-1，fms-like tyrosine kinase 1，fms样酪氨酸激酶1）， VEGFR2（KDR，kinase insert domain，激酶插入结构域；或Flk-1，fetal liver kinase 1，胎儿肝激酶1），在血管和淋巴管内皮细胞上表达， VEGFR3（也称为Flt-4）仅限于淋巴管内皮细胞。不同的VEGF对应不同的VEGFR，在这里最常见的其实是VEGFR
PriCells: Primary cells culture with supplement of vascular endothelial growth factor (VEGF)
spanning region, and an intracellular portion containing a split tyrosine-kinase domain. VEGF-A binds to VEGFR-1 (Flt-1) and VEGFR-2 (KDR/Flk-1). VEGFR-2 appears to mediate almost all of the known cellular responses to VEGF. The function of VEGFR
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