SOCS1 antibody
Product Name SOCS1 antibody
Catalog No PAab09926
Packing 100ul
Form liquid
Alternative Name CIS1, CISH1, JAB, SOCS-1, SSI-1, SSI1, TIP3
Purification Immunogen affinity purified
Purity 95% as determined by SDS-PAGE
Host Rabbit
Isotype IgG
Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)
Background/ FUNCTION
This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN)-gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival.
Immunogen Suppressor of cytokine signaling 1
Specificity Human, Mouse, Rat
Tested Application ELISA, WB
Recommended dilution WB: 1:500 - 1:2000
IHC use
WB use
mouse lung were subjected to SDS PAGE followed by western blot with PAab09926 (SOCS1 antibody) at dilution of 1:1000
Protein Information
Gene ID 8651
Uniprot ID O15524
Calculated MW 24 kDa
Research Area Metabolism, Signal Transduction