- ￥2262
- LSM Bio
- 进口
- PAab07887
- 2025年07月16日
- ELISA,IHC,IF,IP,WB
- E. coli - derived recombinant protein
- Human,Mouse ,Rat
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
SIX homeobox 2
- 亚型：
IgG
- 形态：
liquid
- 保存条件：
负20摄氏度
- 克隆性：
Polyclonal antibody
- 标记物：
Non-conjugated
- 适应物种：
Human,Mouse ,Rat
- 保质期：
6个月
- 抗原来源：
Rabbit
- 目录编号：
P67936
- 级别：
纯化级别
- 库存：
50
- 供应商：
LSM bio
- 宿主：
E. coli - derived recombinant protein
- 应用范围：
ELISA,IHC,IF,IP,WB
- 浓度：
≥95% as determined by SDS-PAGE
- 靶点：
SIX homeobox 2
- 抗体英文名：
anti-SIX2 antibody,SIX2 antibody
- 抗体名：
anti-SIX2 抗体,SIX2 抗体
- 规格：
100μg
SIX2抗体| SIX2 antibody
货号 PAab07887
蛋白别名
蛋白介绍
Transcription factor that plays an important role in the development of several organs, including kidney, skull and stomach. During kidney development, maintains cap mesenchyme multipotent nephron progenitor cells in an undifferentiated state by opposing the inductive signals emanating from the ureteric bud and cooperates with WNT9B to promote renewing progenitor cells proliferation. Acts through its interaction with TCF7L2 and OSR1 in a canonical Wnt signaling independent manner preventing transcription of differentiation genes in cap mesenchyme such as WNT4. Also acts independently of OSR1 to activate expression of many cap mesenchyme genes, including itself, GDNF and OSR1. During craniofacial development plays a role in growth and elongation of the cranial base through regulation of chondrocyte differentiation. During stomach organogenesis, controls pyloric sphincter formation and mucosal growth through regulation of a gene network including NKX2-5, BMPR1B, BMP4, SOX9 and GREM1. During branchial arch development, acts to mediate HOXA2 control over the insulin-like growth factor pathway. Also may be involved in limb tendon and ligament development (By similarity). Plays a role in cell proliferation and migration.
产品描述
anti-SIX2 antibody is a Rabbit Polyclonal antibody againstSIX2..
建议稀释比例
IHC
Immunohistochemistry of paraffin-embedded human kidney using PAab07887(SIX2 antibody) at dilution of 1:50
Western blot
HEK-293 cells were subjected to SDS PAGE followed by western blot with PAab07887( SIX2 Antibody) at dilution of 1:600(本抗体仅供体外科研用途，不可用于临床诊断!) "">
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文献和实验： 由硅羟基与硅烷化试剂反应而得。 具有良好的热稳定性和化学稳定性，能在 PH=2～8 的介质中使用，目前占绝对优势。 1、单官能团有机硅烷。 2、双官能团有机硅烷： 双官能团化合物（如 R2SiX2）可单独形成线型或环状有机硅氧烷。 3、三官能团有机硅烷： 硅烷化试剂中三个 X 基团都参与硅醇基反应的可能性很小。 三官能团化合物（如 RSiX3）反应后的产物可水解进一步形成硅羟基，进而形成三维交联化合物。 4、聚合层键合相： 在硅胶表面与硅烷
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