- ￥2262
- LSM Bio
- 进口
- PAab07881
- 2025年07月18日
- ELISA,WB
- E. coli - derived recombinant protein
- Human,Mouse ,Rat
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
sirtuin (silent mating type information regulation 2 homolog) 3 (S. cerevisiae)
- 亚型：
IgG
- 形态：
liquid
- 保存条件：
负20摄氏度
- 克隆性：
Polyclonal antibody
- 标记物：
Non-conjugated
- 适应物种：
Human,Mouse ,Rat
- 保质期：
6个月
- 抗原来源：
Rabbit
- 目录编号：
P67936
- 级别：
纯化级别
- 库存：
50
- 供应商：
LSM bio
- 宿主：
E. coli - derived recombinant protein
- 应用范围：
ELISA,WB
- 浓度：
≥95% as determined by SDS-PAGE
- 靶点：
sirtuin (silent mating type information regulation 2 homolog) 3 (S. cerevisiae)
- 抗体英文名：
anti-SIRT3 antibody,SIRT3 antibody
- 抗体名：
anti-SIRT3 抗体,SIRT3 抗体
- 规格：
100μg
SIRT3抗体| SIRT3 antibody
货号 PAab07881
蛋白别名 SIR2L3
蛋白介绍
NAD-dependent protein deacetylase. Activates or deactivates mitochondrial target proteins by deacetylating key lysine residues. Known targets include ACSS1, IDH, GDH, SOD2, PDHA1, LCAD, SDHA and the ATP synthase subunit ATP5O. Contributes to the regulation of the cellular energy metabolism. Important for regulating tissue-specific ATP levels.
产品描述
anti-SIRT3 antibody is a Rabbit Polyclonal antibody againstSIRT3..
建议稀释比例
IHC
Western blot
(本抗体仅供体外科研用途，不可用于临床诊断!) "">
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文献和实验In Vivo Measurement of the Acetylation State of Sirtuin Substrates as a Proxy for Sirtuin Activity
acetylation status of select sirtuin substrates in vivo remains an important tool for evaluating changes in sirtuin activity. Here, we describe how to perform the analysis of the acetylation status of key SIRT1 and SIRT3 targets in rodent tissues and cultured
Chemical Acetylation and Deacetylation
acetylation on protein lysine residues is characterized by native gel electrophoresis and Western blotting. Acetyl-Lys modifications are then examined for deacetylation using a SIRT3 deacetylase activity assay and followed by stable isotope dilution mass
Oxygen Flux Analysis to Understand the Biological Function of Sirtuins
The sirtuins are a family of highly conserved NAD+ -dependent lysine deacylases with important roles in metabolic regulation. Of the seven mammalian sirtuins, three localize to the mitochondria: SIRT3, SIRT4, and SIRT5. Mitochondrial sirtuins
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