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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
2'-5'-oligoadenylate synthetase 3, 100kDa
- 亚型:
IgG
- 形态:
liquid
- 保存条件:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
- 克隆性:
单克隆
- 适应物种:
Human
- 保质期:
12 month
- 库存:
50
- 供应商:
LSM bio
- 宿主:
Rabbit
- 应用范围:
ELISA,WB,IHC,IF
- 浓度:
≥95% as determined by SDS-PAGE
- 抗体英文名:
anti-OAS3 antibody,OAS3 antibody
- 抗体名:
anti-OAS3 抗体,OAS3 抗体
- 规格:
100μg
OAS3抗体| OAS3 antibody
货号 PAab05952
蛋白别名
蛋白介绍
Interferon-induced, dsRNA-activated antiviral enzyme which plays a critical role in cellular innate antiviral response. In addition, it may also play a role in other cellular processes such as apoptosis, cell growth, differentiation and gene regulation. Synthesizes preferentially dimers of 2'-5'- oligoadenylates (2-5A) from ATP which then bind to the inactive monomeric form of ribonuclease L (RNase L) leading to its dimerization and subsequent activation. Activation of RNase L leads to degradation of cellular as well as viral RNA, resulting in the inhibition of protein synthesis, thus terminating viral replication. Can mediate the antiviral effect via the classical RNase L-dependent pathway or an alternative antiviral pathway independent of RNase L. Displays antiviral activity against Chikungunya virus (CHIKV), Dengue virus, Sindbis virus (SINV) and Semliki forest virus (SFV).
产品描述
anti-OAS3 antibody is a Rabbit Polyclonal antibody againstOAS3..
建议稀释比例
IHC
Immunohistochemistry of paraffin-embedded human skin cancer tissue slide using PAab05952( OAS3 Antibody) at dilution of 1:50
Western blot
A375 cells were subjected to SDS PAGE followed by western blot with PAab05952(OAS3 antibody) at dilution of 1:800(本抗体仅供体外科研用途,不可用于临床诊断!)
武汉维克赛思科技有限公司
地址:武汉东湖新技术开发区东信路光谷创业街10栋
联系人:童经理
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