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- 详细信息
- 询价记录
- 文献和实验
- 技术资料
- 免疫原:
chondroitin sulfate proteoglycan 4
- 亚型:
IgG
- 形态:
liquid
- 保存条件:
负20摄氏度
- 克隆性:
Polyclonal antibody
- 标记物:
Non-conjugated
- 适应物种:
Human,Mouse ,Rat
- 保质期:
6个月
- 抗原来源:
Rabbit
- 目录编号:
Q9GZT9
- 级别:
纯化级别
- 库存:
50
- 供应商:
LSM bio
- 宿主:
E. coli - derived recombinant protein
- 应用范围:
ELISA,WB,IHC
- 浓度:
≥95% as determined by SDS-PAGE
- 靶点:
CSPG4,NG2
- 抗体英文名:
anti-CSPG4,NG2 antibody,CSPG4,NG2 antibody
- 抗体名:
anti-CSPG4,NG2 抗体,CSPG4,NG2 抗体
- 规格:
100μg
CSPG4,NG2抗体| CSPG4,NG2 antibody
货号 PAab02025
蛋白别名 CSPG4 antibody, HMW MAA antibody, MCSP antibody, MCSPG antibody, MEL CSPG antibody, MSK16 antibody, NG2
蛋白介绍
CSPG4, also named as HMW-MAA, MCSP, MCSPG, MEL-CSPG, MSK16 and NG2, is a proteoglycan playing a role in cell proliferation and migration which stimulates endothelial cells motility during microvascular morphogenesis. CSPG4 may inhibit neurite outgrowth and growth cone collapse during axon regeneration. It is cell surface receptor for collagen alpha 2(VI) which may confer cells ability to migrate on that substrate. CSPG4 may regulate MPP16-dependent degradation and invasion of type I collagen participating in melanoma cells invasion properties. It modulates the plasminogen system by enhancing plasminogen activation and inhibiting angiostatin.
产品描述
anti-CSPG4,NG2 antibody is a Rabbit Polyclonal antibody againstCSPG4,NG2..
建议稀释比例
WB : 1:500-1:5000 IHC : 1:50-1:500
IHC
Immunohistochemistry of paraffin-embedded human lung cancer tissue slide using PAab02025( CSPG4,NG2 Antibody) at dilution of 1:200 heat mediated antigen retrieved with Tris-EDTA buffer(pH9).
Western blot
A375 cells were subjected to SDS PAGE followed by western blot with PAab02025(CSPG4,NG2 antibody) at dilution of 1:300(本抗体仅供体外科研用途,不可用于临床诊断!)
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- 作者
- 内容
- 询问日期
文献和实验Detection of Chondroitin Sulfate Proteoglycan 4 (CSPG4) in Melanoma
The tumor antigen chondroitin sulfate proteoglycan 4 (CSPG4) appears to be a useful biomarker to identify melanoma cells and an attractive target to apply antibody-based immunotherapy for the treatment of melanoma. Here we described
有效抑制肿瘤术后复发!浙大顾臻等开发神奇水凝胶,实现缓释型免疫疗法
细胞和免疫检查点阻断可能是提高 CAR-T 细胞在实体肿瘤中作用的方式。 主要研究内容 新型水凝胶的开发 研究人员以丙烯酸酯基修饰的透明质酸 (HA) 为原料,通过交联剂和光引发剂在紫外光照射下进行交联,然后将靶向 CSPG4 抗原(黑色素瘤特异性抗原)的 CAR-T 细胞和抗 PDL1 阻断抗体结合的人血小板 (P-aPDL1) 装载到水凝胶中。为了支持 CAR-T 细胞在水凝胶中的生存能力和增殖,PLGA 纳米颗粒包装的细胞因子 IL-15 也被纳入。共聚焦显微镜和低温扫描电镜证实了 P-aPDL
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