重组人检查点蛋白(HUS1)北京厂家

特别提示：包括重组人检查点蛋白(HUS1)在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：重组人检查点蛋白(HUS1)
英文名称：Recombinant Human Checkpoint Protein HUS1
产品货号：JN0900
产品规格：10μg|50μg|500μg|1mg

本品由我们的大肠杆菌表达系统制备而成，目的基因编码的Met1-Ser280在N端含有His标签。

HUS1质量控制：＞95%(还原性SDS-PAGE)

HUS1制剂：液体

HUS1保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于HUS1：
Checkpoint protein HUS1 is a member of the HUS1 family, members of which are shuttled between the nucleus and cytoplasm. HUS1 is expressed in many tissues. HUS1 is a component of an evolutionarily conserved, genotoxin-activated checkpoint complex involved in arresting the cell cycle in response to DNA damage. DNA damage induced chromatin binding has been shown to depend on the activation of the checkpoint kinase ATM, and is thought to be an early checkpoint signaling event. HUS1 binds with Rad9 and Rad1 to form the 9-1-1 (RAD9-RAD1-HUS1) complex, which localizes to DNA lesions and promotes DNA damage signaling and repair or apoptosis and cell cycle arrest.

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