重组人CD105(Endoglin)现货供应

特别提示：包括重组人CD105(Endoglin)在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：重组人CD105(Endoglin)
英文名称：Recombinant Human Endoglin
产品货号：JN1878
产品规格：10μg|50μg|500μg|1mg

本品由我们的大肠杆菌表达系统制备而成，目的基因编码的Glu26-Gln176在N端含有Trx标签和His标签。

CD105/Endoglin质量控制：＞95%(还原性SDS-PAGE)

CD105/Endoglin制剂：液体

CD105/Endoglin保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于CD105/Endoglin：
Endoglin is a single-pass type I membrane protein which restricted to endothelial cells in all tissues except bone marrow. Endoglin as major glycoprotein of vascular endothelium, it has been found on endothelial cells, activated macrophages, fibroblasts, and smooth muscle cells. Furthermore, Homodimer forms a heteromeric complex with the signaling receptors for transforming growth factor-beta: TGFBR1 and/or TGFBR2. It may have an important role in the binding of endothelial cells to integrins and/or other RGD receptors. Defects in ENG are the cause of hereditary hemorrhagic telangiectasia type 1 (HHT1), which is an autosomal dominant multisystemic vascular dysplasia, characterized by recurrent epistaxis, muco-cutaneous telangiectases, gastro-intestinal hemorrhage, and pulmonary (PAVM), cerebral (CAVM) and hepatic arteriovenous malformations.

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