Human Integrin alpha 9 beta 1

内毒素:
Less than 1.0 EU per μg by the LAL method.

纯度:
>95% as determined by SDS-PAGE.

活性:
n/a

产品背景:
Integrin alpha 9 beta 1 is one of twelve integrin family adhesion receptors that share the beta 1 (CD29) subunit. It is the non-covalent heterodimer of 150 kDa alpha 9 and 130 kDa beta 1 type I transmembrane glycoprotein subunits. The integrin alpha 9 beta 1 mediates cell adhesion to tenascin-C and VCAM-1 by binding to sequences distinct from the common integrin-recognition sequence, arginine-glycine-aspartic acid (RGD). A thrombin-cleaved NH(2)-terminal fragment of osteopontin containing the RGD sequence has recently been shown to also be a ligand for integrin alpha 9 beta 1.

产品描述:
Human ITGA9 & ITGB1 Heterodimer Protein, produced by co-expression of ITGA9 and ITGB1, has a calculated MW of 111.1 kDa (ITGA9) & 82.7 kDa (ITGB1). Subunit ITGA9 is fused with an acidic tail at the C-terminus and followed by a polyhistidine tag and subunit ITGB1 contains no tag but a basic tail at the C-terminus. The reducing (R) protein migrates as 130 kDa (ITGA9) and 110 kDa (ITGB1) respectively due to glycosylation.
因为难以在供应系统上进行数据同步//所以了解更多产品规格及产品数据//请移步：
http://www.acrobiosystems.cn/P1401-Human_Integrin_alpha_9_beta_1_%28ITGA9%26ITGB1%29_Heterodimer_Protein.html