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X-Cytochrome P450 (scc) a.a. 509-526
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文献和实验Analysis of Trophoblast Giant Cell Steroidogenesis in Primary Cultures
to analyze the regulation of genes involved in progesterone biosynthesis in miniature cultures of primary trophoblast cells from rodents. These genes include cholesterol side chain cleavage cytochrome P450 (P450scc) and its accessory proteins, steroidogenic
Estrogen-Deficient Mouse Models in the Study of Brain Injury and Disease
has to be transferred to the site where the cytochrome P450 side-chain cleavage enzyme (P450scc, CYP11A1) is located. As its name indicates, it catalyzes the cleavage of the side-chain of cholesterol (4) to form pregnenolone. Conversion of pregnenolone to estrogens
, to the cytochrome P450 cholesterol side chain cleavage (P450scc) enzyme. The expression of StAR protein is regulated by cAMP-dependent signaling in steroidogenic cells. During the course of our studies in mouse Leydig cells, we employ several methods for studying
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