Murine CCL11 is belonging to the CC chemokine family.CCL11 was first purified from bronchoalveolar lavage fluid of guinea pigs.It was a strong and specific eosinophil chemoattractant in vitro.It can directly chemotactic for eosinophils,but not for monocytes or neutrophils.Murine CCL11 is approximately 63%identical at the amino acid level to human CCL11.In addition,CCL11 also shows about 60%amino acid sequence identity to human MCPs.CCR3 has been identified to be a specific CCL11 receptor.
使用说明
This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.
技术规格
外观
Sterile Filtered White lyophilized(freeze-dried)powder.
纯度
>96%by SDS-PAGE and HPLC analyses.
来源
Escherichia coli.
生物活性
Fully biologically active when compared to standard.The biological activity determined by a chemotaxis bioassay using purified eosinophils is in a concentration range of 100-1000ng/ml.
成分
Lyophilized from a 0.2μmfiltered concentrated solution in PBS,pH 7.4.
内毒素
Less than 1 EU/μg of rMuEotaxin/CCL11 as determined by LAL method.
复溶
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20?C.Further dilutions should be made in appropriate buffered solutions.