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- 详细信息
- 技术资料
- 保存条件:
4°C, sealed storage, away from moisture
- 英文名:
BVD-523 hydrochloride; VRT752271 hydrochloride
- 库存:
货期:1-2天
- 供应商:
MedChemExpress LLC
- CAS号:
1956366-10-1
- 规格:
10 mM * 1 mL/5 mg/10 mg/50 mg
| 规格: | 10 mM * 1 mL | 产品价格: | ¥990.0 |
|---|---|---|---|
| 规格: | 5 mg | 产品价格: | ¥900.0 |
| 规格: | 10 mg | 产品价格: | ¥1600.0 |
| 规格: | 50 mg | 产品价格: | ¥4800.0 |
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Ulixertinib hydrochloride
CAS No. : 1956366-10-1
MCE 国际站:Ulixertinib hydrochloride
产品活性:Ulixertinib hydrochloride (BVD-523 hydrochloride) 是一种有效、可口服、高度选择性、ATP-竞争性、可逆、共价的 ERK1/2 抑制剂,对 ERK2 的 IC50 值 <0.3 nM。Ulixertinib hydrochloride 同时可抑制 ERK2 和 下游蛋白 RSK 的磷酸化。
研究领域:MAPK/ERK Pathway | Stem Cell/Wnt
作用靶点:ERK
In Vitro: Combined Ulixertinib (BVD-523; 10, 20, 30 μM; 48 hours) and VS-5584 treatment causes significant induction of cell death in human pancreatic cancer (HPAC) cells in PDAC cell lines BxPC-3, MIAPaCa-2, and CFPAC-1.
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