VU591,1315380-70-1

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VU591 hydrochloride

CAS No. : 1315380-70-1

MCE 国际站：VU591 hydrochloride

产品活性：VU591 hydrochloride 是一种强效的、选择性的肾外髓钾通道 (ROMK 或Kir1.1) 的抑制剂，其 IC₅₀ 值为 0.24 μM。VU591 hydrochloride 和它的等效物 HY-108585A 可用于神经领域的研究。

研究领域：Membrane Transporter/Ion Channel

作用靶点：Potassium Channel

In Vitro: VU591 hydrochloride is a selective ROMK inhibitor and a ROMK channel pore blocker. VU591 can bind serum protein and has high metabolic stability.

In Vivo: VU591 hydrochloride (i.c.v.; 1.842 μg) significantly decreases the immobile time in TST.

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