重组小鼠RANK(TNFRSF11A)(CD265)

特别提示：包括重组小鼠RANK(TNFRSF11A)(CD265)在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：重组小鼠RANK(TNFRSF11A)(CD265)
英文名称：Recombinant Mouse Receptor Activator of NF-kappa B
产品货号：JN0509
产品规格：10μg|50μg|500μg|1mg

本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Val31-Ser214在C端含有His标签。

RANK/TNFRSF11A/CD265质量控制：＞95%(还原性SDS-PAGE)

RANK/TNFRSF11A/CD265制剂：冻干品

RANK/TNFRSF11A/CD265保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

RANK/TNFRSF11A/CD265复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于RANK/TNFRSF11A/CD265：
Receptor activator of NF-κB(RANK,TNFRSF11A) belongs to one member oftumor necrosis factor receptor family.It is a receptor for TNFSF11/RANKL/TRANCE/OPGL. This gene encodes a type 1 membrane protein with a 30 amino acids (aa) signal peptide, 184 aa extracellular region , a 20 aa transmembrane domain and a 391 aa cytoplasmic region. Human and murine RANK share 81% aa identity in their extracellular domains. RANK is ubiquitous highly expressed in trabecular bone, thymus, small intestine, lung, brain and kidney, but weakly expressed in spleen and bone marrow. After binding its ligand RANKL, RANK can activate signaling pathways such as NF-κB, JNK, ERK, p38, and Akt/PKB, through TRAF protein phosphorylation. RANK/TNFRSF11A signaling is largely considered to be growth promoting and apoptosis reducing such as the effects observed in osteoclasts. RANK/TNFRSF11A was also found to be involved in the regulation of interactions between T-cells and dendritic cells.

我公司销售的重组小鼠RANK(TNFRSF11A)(CD265)，rmTNFRSF11A，重组RANK，rmRANK，重组CD265，重组小鼠TNFRSF11A，rmCD265，rTNFRSF11A，重组TNFRSF11A，重组Receptor Activator of NF-kappa B，重组小鼠CD265，重组小鼠RANK，重组小鼠Receptor Activator of NF-kappa B，rRANK，Recombinant Mouse Receptor Activator of NF-kappa B，rCD265质量上佳，价格普惠，欢迎广大新老客户踊跃订购。