重组人EMAP-II报价

特别提示：包括重组人EMAP-II在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：重组人EMAP-II
英文名称：Recombinant Human Endothelial-Monocyte Activating Polypeptide II
产品货号：GS4445
产品规格：5μg

分子量：Approximately 18.2kDa,a single non-glycosylated polypeptide chain containing 166 amino acids.
储存条件：冷冻（-20℃）

概述

Endothelial-Monocyte Activating Polypeptide II(EMAP-II)is a tumor derived cytokine that exerts a wide range of activities on endothelial cells,monocytes and neutrophils.EMAP-II inhibits endothelial cell proliferation,vasculogenesis,neovessel formation,and can induce apoptosis.It is also chemotactic towards neutrophils and monocytes and induces myeloperoxidase activity from neutrophils.Of clinical importance,EMAP-II inhibits angiogenesis of vascular beds and suppresses the growth of primary and secondary tumors without affecting normal tissues.Mature EMAP-II is an 18.3 kDa protein,which is synthesized as the C-terminal portion of a biologically inactive precursor protein containing a propeptide of 146 amino acid residues.

使用说明

This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.

技术规格
 

外观	Sterile Filtered White lyophilized(freeze-dried)powder.
纯度	＞98%by SDS-PAGE and HPLC analyses.
来源	Escherichia coli.
生物活性	Fully biologically active when compared to standard.The ED50 as determined by the apoptotic effect using serum free human MCF-7 cells is less than 40ng/ml,corresponding to a specific activity of>2.5×104 IU/mg.
成分	Lyophilized from a 0.2μmfiltered concentrated solution in PBS,pH 7.4.
内毒素	Less than 1 EU/μg of rHuEMAP-II as determined by LAL method.
复溶	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20 ℃.Further dilutions should be made in appropriate buffered solutions.
氨基酸序列	SKPIDVSRLD LRIGCIITAR KHPDADSLYV EEVDVGEIAP RTVVSGLVNH VPLEQMQNRM VILLCNLKPA KMRGVLSQAM VMCASSPEKI EILAPPNGSV PGDRITFDAF PGEPDKELNP KKKIWEQIQP DLHTNDECVA TYKGVPFEVK GKGVCRAQTM SNSGIK

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