重组人Rb,137a.a.北京厂家

特别提示：包括重组人Rb,137a.a.在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：重组人Rb,137a.a.
英文名称：Recombinant Human Retinoblastoma-Associated Protein Fragment, 137a.a. with His-tag
产品货号：GS4639
产品规格：10μg

分子量：Approximately 16.5kDa,a single non-glycosylated polypeptide chain containing 146 amino acids.
储存条件：冷冻（-20℃）

概述

Rb encoded by the RB1 gene in humans,is expressed by retina and belongs to the etinoblastoma-associated protein family.The hole protein consists of 928 a.a.and the rHuRb fragment occupies sequence of 792-929 a.a..Rb is a key regulator of entry into cell division that acts as a tumor suppressor.It has many functions,for example,promotes G0-G1 transition when phosphorylated by CDK3/cyclin-C,and acts as a transcription repressor of E2F1 target genes and so on.The rHuRb is the region that rich of modified residue like phosphothreonine and N6-acetyllysine.

使用说明

This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.

技术规格
 

外观	Sterile Filtered White lyophilized(freeze-dried)powder.
纯度	＞95%by SDS-PAGE and HPLC analyses.
来源	Escherichia coli.
成分	Lyophilized from a 0.2μmfiltered concentrated solution in PBS,pH 7.4.
内毒素	Less than 1 EU/μg of rHuRb137,His as determined by LAL method.
复溶	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at<-20 ℃.Further dilutions should be made in appropriate buffered solutions.
氨基酸序列	MASFPSSPLR IPGGNIYISP LKSPYKISEG LPTPTKMTPR SRILVSIGES FGTSEKFQKI NQMVCNSDRV LKRSAEGSNP PKPLKKLRFD IEGSDEADGS KHLPGESKFQ QKLAEMTSTR TRMQKQKMND SMDTSNKEEK HHHHHH

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