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- 详细信息
- 文献和实验
- 技术资料
- 库存:
204
- 英文名:
Recombinant Rhesus Macaque Granulocyte-Macrophage Colony Stimulating Factor
- 保质期:
长期
- 供应商:
北京百奥莱博科技有限公司
- 保存条件:
冷冻(-20℃)
- 规格:
2μg
特别提示:包括重组猴GM-CSF在内,本公司的所有产品仅可用于科研实验,严禁用于临床医疗及其他非科研用途!
产品名称:重组猴GM-CSF
英文名称:Recombinant Rhesus Macaque Granulocyte-Macrophage Colony Stimulating Factor
产品货号:GS4459
产品规格:2μg
分子量:Approximately 14.4kDa,a single non-glycosylated polypeptide chain containing 127 amino acids.
储存条件:冷冻(-20℃)
概述
Granulocyte-Macrophage Colony Stimulating Factor(GM-CSF)is secreted by a number of different cell types(including activated T cells,B cells,macrophages,mast cells,endothelial cells and fibroblasts)in response to cytokine or immune and inflammatory stimulation.It was initially characterized as a growth factor that can support the in vitro colony formation of granulocyte-macrophage progenitors and has functions of stimulates the growth and differentiation of hematopoietic precursor cells from various lineages.GM-CSF has also been reported to have a functional role on non-hematopoietic cells and can induce human endothelial cells to migrate and proliferate.Additionally,it can stimulate the proliferation of a number of tumor cell lines,including osteogenic sarcoma,carcinoma and adenocarcinoma cell lines.It is reported that GM-CSF has no biological effects across species.
使用说明
This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.
技术规格
| 外观 | Sterile Filtered White lyophilized(freeze-dried)powder. |
| 纯度 | >98%by SDS-PAGE and HPLC analyses. |
| 来源 | Escherichia coli. |
| 生物活性 | Fully biologically active when compared to standard.The ED50 as determined by a cell proliferation assay using human TF-1 cells is less than 0.1ng/ml,corresponding to a specific activity of>1.0×107 IU/mg. |
| 成分 | Lyophilized from a 0.2μmfiltered concentrated solution in PBS,pH 7.4. |
| 内毒素 | Less than 1 EU/μg of rRhGM-CSF as determined by LAL method. |
| 复溶 | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20 ℃.Further dilutions should be made in appropriate buffered solutions. |
| 氨基酸序列 | APARSPSPGT QPWEHVNAIQ EARRLLNLSR DTAAEMNKTV EVVSEMFDLQ EPSCLQTRLE LYKQGLQGSL TKLKGPLTMM ASHYKQHCPP TPETSCATQI ITFQSFKENL KDFLLVIPFD CWEPVQE |
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