重组大鼠IL-9北京品牌

特别提示：包括重组大鼠IL-9在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：重组大鼠IL-9
英文名称：Recombinant Rat Interleukin-9
产品货号：GS4708
产品规格：2μg

分子量：Approximately 14.3kDa,a single non-glycosylated polypeptide chain containing 127 amino acids.
储存条件：冷冻（-20℃）

概述

Interleukin-9(IL-9)is encoded by the IL9 gene and produced by T-cells and specifically by CD4+ helper cells.IL-9 was originally identified as a cytokine found in the conditioned medium of a human T cell leukemia virus type I(HTLVI)transformed T cell line.It functions through the IL-9 receptor,which activates different signal transducer and activator(STAT)proteins and thus connects this cytokine to various biological processes.IL-9 can support the growth of IL-2 independent and IL-4 independent helper T-cells.Rat IL-9 has approximately 73%amino acid sequence identity with murine IL-9.The gene encoding this cytokine has been identified as a candidate gene for asthma.Genetic studies on a mouse model of asthma demonstrated that this cytokine is a determining factor in the pathogenesis of bronchial hyperresponsiveness.

使用说明

This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.

技术规格
 

外观	Sterile Filtered White lyophilized(freeze-dried)powder.
纯度	＞97%by SDS-PAGE and HPLC analyses.
来源	Escherichia coli.
生物活性	Fully biologically active when compared to standard.The ED50 as determined by a cell proliferation assay using murine TS1 cells is less than 10ng/ml,corresponding to a specific activity of>1.0×105 IU/mg.
成分	Lyophilized from a 0.2μmfiltered concentrated solution in PBS,pH 7.4.
内毒素	Less than 0.1 EU/μg of rRtIL-9 as determined by LAL method.
复溶	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20 ℃.Further dilutions should be made in appropriate buffered solutions.
氨基酸序列	MQRCSTSWGI QHTSYLIENL KDDPSSKCSC SANVTSCLCL PIPSDDCTTP CFQEGMSQVT NATQQSKFSP FFFRVKRIVE TLKSNKCQFF SCEKPCNQTT AGNTVSFLKS LLKTFQKTEV QVQRSRA

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