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- 武汉
- 2026年01月22日
- WB;IHC;IF
- Rabbit
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- 详细信息
- 文献和实验
- 技术资料
- 抗体英文名：
Lamin B1 Polyclonal Antibody
- 应用范围：
WB;IHC;IF
- 宿主：
Rabbit
- 库存：
99
- 保存条件：
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
- 形态：
液体
- 亚型：
IgG
- 规格：
100μL/25μL
| 规格： | 100μL | 产品价格： | ￥780.0 |
|---|---|---|---|
| 规格： | 25μL | 产品价格： | ￥300.0 |
Lamin B1 Polyclonal Antibody
| Verified Samples |
Verified Samples in WB: HepG2, Rat heart, Mouse kidney, Rat brain, Mouse lung, Mouse spleen
Verified Samples in IHC: Human breast cancer, Mouse liver, Human uterus, Human liver Verified Samples in IF: HepG2 |
| Dilution |
WB 1:250-1:500, IHC 1:200-1:600
|
| Clonality |
Polyclonal
|
| Isotype |
IgG
|
| Immunogen |
Recombinant Rat Lamin-B1 protein expressed by E.coli
|
| Abbre |
Lamin B1
|
| Synonyms |
ADLD, LMN, LMN2, LMNB, LMNB1, Lamin-B1, Lmnb1, MGC111419, OTTHUMP00000159218, lamin B1
|
| Swissprot |
P70615
|
| Calculated MW |
67 kDa
|
| Observed MW |
72 kDa
|
| Cellular Localization |
Nucleus inner membrane.
|
| Concentration |
1 mg/mL
|
| Storage |
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
|
| Buffer |
PBS with 0.05% Proclin300, 1% protective protein and 50% glycerol, pH7.4
|
| Purification Method |
Antigen Affinity Purification
|
| Research Areas |
Cancer, Cell Biology, Signal Transduction, Tags & Cell Markers
|
| Conjugation |
Unconjugated
|
| Background |
The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1. Alternative splicing results in transcript variants and a duplication of this gene is associated with autosomal dominant adult-onset leukodystrophy (ADLD).
|
Lamin B1 Polyclonal AntibodyElabscience®拥有先进的单抗，多抗和流式抗体开发技术平台，提供8500+高品质抗体， 适用于胞内和胞外蛋白的鉴定、定量和定位研究。抗体已在多种应用中得到验证，包含 流式细胞术（Flow Cytometry）、 免疫印迹（WB）、 免疫组化（IHC/ICC）、 免疫（共）沉淀（IP/Co-IP）、 免疫荧光（IF） 等实验。抗体产品涉及多种生命科学研究领域，包括肿瘤、免疫、心血管、细胞生物学、神经科学、表观遗传学等。Elabscience®始终致力于提高抗体的质量和种类，以保障并加快您的研究进程。
Lamin B1 Polyclonal AntibodyStore at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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文献和实验Polyclonal Antibody Production
, if desired this is best accomplished by Protein A Affinity Chromatography. 上一篇：make an Antibody against a Peptides 下一篇：Immunization Protocol for Monoclonal Antibody Production
Discovery of Lamin B1 and Vimentin as Circulating Biomarkers for Early Hepatocellular Carcinoma
electrophoresis (2DE) and MALDI-TOF/TOF mass spectrometry, our groups have identified lamin B1 (LMNB1) and vimentin (VIM) as promising biomarkers for detection of early HCC. Protein levels of both biomarkers were significantly elevated in cancerous tissues
Polyclonal Antibody Production
Polyclonal Antibody Production Very useful for rapid and simple generation of antibodies for western blots, ELISA assays, and immunoprecipitation. Rabbit Immunization Initial Preparation Your antigen
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