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- 详细信息
- 文献和实验
- 技术资料
- 抗体名:
(KO Validated) Caspase-3 Polyclonal Antibody_货号:E-AB-60646_多克隆抗体
- 抗体英文名:
(KO Validated) Caspase-3 Polyclonal Antibody
- 应用范围:
WB;IHC
- 宿主:
Rabbit
- 适应物种:
Human;Mouse;Rat
- 保质期:
12个月
- 目录编号:
E-AB-60646
- 级别:
科研级别
- 库存:
999
- 供应商:
武汉伊莱瑞特生物科技股份有限公司
- 标记物:
Unconjugated
- 克隆性:
Polyclonal
- 保存条件:
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
- 形态:
液体
- 亚型:
IgG
- 规格:
200μL/120μL/60μL
| 规格: | 200μL | 产品价格: | ¥4020.0 |
|---|---|---|---|
| 规格: | 120μL | 产品价格: | ¥2520.0 |
| 规格: | 60μL | 产品价格: | ¥1580.0 |
货号:E-AB-60646
| Verified Samples |
Verified Samples in WB:Jurkat,293T
Verified Samples in IHC:Rat spleen,Human tonsil |
| Dilution |
WB 1:500-1:2000, IHC 1:50-1:200
|
| Clonality |
Polyclonal
|
| Isotype |
IgG
|
| Immunogen |
Recombinant fusion protein of human Caspase-3 (NP_004337.2).
|
| Abbre |
Caspase-3
|
| Synonyms |
CPP32;CPP32B;SCA-1;Active Caspase 3;CASP3;active Caspase-3;Caspase 3;Caspase-3 p12;caspase-3抗体
|
| Swissprot |
P42574
|
| Calculated MW |
31kDa
|
| Observed MW |
17kDa/35kDa
|
| Cellular Localization |
Cytoplasm.
|
| Concentration |
1mg/mL
|
| Storage |
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
|
| Buffer |
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
|
| Purification Method |
Affinity purification
|
| Research Areas |
Cancer; Cell Biology; Metabolism; Neuroscience
|
| Conjugation |
Unconjugated
|
| Background |
This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein.
|
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文献和实验自2012年第一篇引用文献问世,至2023年8月,Elabscience已协助各地科研工作者发表超13,000篇SCI文献,包括行业顶/级期刊Nature Medicine, Nature, Cell, Signal Transduction and Targeted Therapy, Circulation, Molecular Cancer, Immunity, Advanced Materials等,总影响因子(IF)59472.59,其中IF≥30的文献超30篇,最高影响因子为66.849,发文单位包含北京大学、中国科学技术大学、浙江大学、斯坦福大学、耶鲁大学、柏林夏里特大学等国内外各大高校。
每年引用文献数量持续增长,保持逐年30%+高增长率,可以预见,Elabscience产品将帮助更多科研工作者发表高质量SCI论文。
文献详情查看>>>>


Construction of Polyclonal Antibody Libraries Using Phage Display
Polyclonal antibody libraries (PCALs) are standardized mixtures of antibodies (Abs) specific for an antigen (Ag) or multi-Ag target (a poly-Ag). As the immunoglobulin (Ig) genes are cloned, the mixtures can be perpetuated, amplified
and how they were validated for use in the system under study (i.e. assay and species)。类似对抗体验证(抗体特异性)的质疑不再仅限于 science,nature 等高分杂志,由于生物试剂普遍存在的特异性问题导致实验结果不可重复1,已经引起主流学术期刊的关注。编辑们正逐渐提高对抗体特异性问题的重视,并要求提供抗体特异性的证据。事实上,抗体的特异性问题,就是我们常说的「脱靶」。市面上抗体的品质良莠不齐,有相当一部分抗体并不能正确识别您想研究的靶标。想想是不是
因此,综合来说,EarthOx的GST标签抗体 (货号#E022040)是一款同时具有高特异性、高灵敏度、多应用类型以及性价比的GST标签抗体。同时,我们也提供其他品牌的GST标签抗体,如Proteintech的GST多克隆抗体 ――GST PolyClonal Antibody(货号#10000-0-AP)以及Abcam、Santa等多种GST标签抗体产品。更多GST标签抗体以及其他如His、HA、Myc、GFP、Flag等其他标签抗体,请电话垂询。美国EarthOx品牌是一家提供高性价比免疫学和细胞
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