LCN2 多克隆抗体

Western Blot（WB）已验证样本:DU145,HT29,BxPC-3,Mouse spleen
免疫荧光（IF）已验证样本:Mouse kidney

WB 1:500-1:2000, IF 1:50-1:200

Polyclonal

IgG

Recombinant fusion protein of human LCN2 (NP_005555.2).

LCN2

LCN2;24p3;MSFI;NGAL;p25抗体

P80188

22kDa

22kDa

Secreted. Upon binding to the SLC22A17 (24p3R) receptor, it is internalized.

1mg/mL

在-20℃下储存有效期为12个月。 避免冻融循环。

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Affinity purification

Cancer; Cardiovascular; Metabolism; Immunology; Signal Transduction

Unconjugated

This gene encodes a protein that belongs to the lipocalin family. Members of this family transport small hydrophobic molecules such as lipids, steroid hormones and retinoids. The protein encoded by this gene is a neutrophil gelatinase-associated lipocalin and plays a role in innate immunity by limiting bacterial growth as a result of sequestering iron-containing siderophores. The presence of this protein in blood and urine is an early biomarker of acute kidney injury. This protein is thought to be be involved in multiple cellular processes, including maintenance of skin homeostasis, and suppression of invasiveness and metastasis. Mice lacking this gene are more susceptible to bacterial infection than wild type mice.