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MedChemExpress LLC
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1 mg/5 mg
| 规格: | 1 mg | 产品价格: | ¥1100.0 |
|---|---|---|---|
| 规格: | 5 mg | 产品价格: | ¥3900.0 |
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PKG Substrate
MCE 国际站:PKG Substrate
产品活性:PKG Substrate 是一种 cGMP 依赖性的蛋白激酶 (PKG) 的选择性底物。
研究领域:Others
作用靶点:Others
In Vitro: Incorporation of [33P]ATP into the synthetic peptide PKG substrate RKRSRAE is measured. N6-benzyl-ATP inhibits kinase activity of PKG Iα gatekeeper mutants but not WT. The serotonin transporter (SERT) is responsible for reuptake of serotonin (5-hydroxytryptamine) after its exocytotic release from neurons. SERT is regulated by several processes, including a cyclic GMP signaling pathway involving nitric oxide synthase, guanylyl cyclase, and PKG.
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文献和实验Approaches for Monitoring PKG1 Oxidative Activation
cGMP-dependent protein kinase, also known as protein kinase G (PKG), is activated independently of cGMP by a novel thiol-reactive mechanism involving the formation of an intermolecular disulfide. This oxidative modification within PKG
接受酶的作用引起化学反应的物质称为该酶(或其酶的反应)的底物。例如淀粉是淀粉酶的底物。过氧化氢是过氧化氢酶的底物。酶反应为可逆时,生成物也是逆反应的底物。此外辅酶也是酶的底物之一。有时候称代谢的起始物质为底物,例如某微生物的呼吸底物、发酵底物等。
Regulatory proteases modulate proteomic dynamics with a spectrum of specificities against substrate proteins. Substrate phage display is one of the key methodologies in producing substrate sequence information in vitro. Factor Xa, a key
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