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- 2025年12月05日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
Powder: -20°C, 3 years; 4°C, 2 years.In solvent: -80°C, 6 months; -20°C, 1 month.
- 库存：
货期：1-2天
- 供应商：
MedChemExpress LLC
- CAS号：
1005264-47-0
- 规格：
10 mM * 1 mL/5 mg/10 mg/25 mg/50 mg/100 mg
| 规格： | 10 mM * 1 mL | 产品价格： | ￥595.0 |
|---|---|---|---|
| 规格： | 5 mg | 产品价格： | ￥570.0 |
| 规格： | 10 mg | 产品价格： | ￥990.0 |
| 规格： | 25 mg | 产品价格： | ￥1800.0 |
| 规格： | 50 mg | 产品价格： | ￥2800.0 |
| 规格： | 100 mg | 产品价格： | ￥4500.0 |
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MX69
CAS No. : 1005264-47-0
MCE 国际站：MX69
产品活性：MX69 是一种 MDM2/XIAP 抑制剂，常用于抗癌研究。
研究领域：Apoptosis | Metabolic Enzyme/Protease
作用靶点：MDM-2/p53 | IAP | E1/E2/E3 Enzyme
In Vitro: MX69 blocks the MDM2 protein-XIAP RNA interaction, leading to MDM2 degradation. MX69 shows minimal inhibitory effect on normal human hematopoiesis in vitro and is very well tolerated in animal models. MX69-induced MDM2 downregulation results not only in inhibition of XIAP expression, but also in activation of p53, which contributes to cancer cell apoptosis in vitro.
In Vivo: MX69-induced MDM2 downregulation results in activation of p53 which contributes to inhibition of cancer cell proliferation in vivo.
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文献和实验5.99 5.82 5.69 5.60 5.52 5.46 5.37 5.27 5.17 5.06 4.96 4.85 6 7 6.54 5.89 5.52 5.28 5.12 4.99 4.90 4.82 4.76 4.67 4.57 4.47 4.36 4.25 4.14 7 8 6.06 5.42 5.05 4.82 4.65 4.53 4.43 4.36 4.29 4.20 4.10 4.00 3.89 3.78 3.67 8 9 5.71 5.08 4.72 4.48
27 36 99 02 96 74 30 83 42 90 26 59 21 19 23 52 23 33 12 96 93 02 18 39 07 02 18 36 07 25 99 32 70 23 43 41 23 52 55 99 31 04 49 69 96 10 47 48 45 88 13 41 43 89 20 97 17 14 49 17 44 60 20 50 81 69 31 99 73 68 68 35 81 33 03 76 24 30 12 48 60 18 99
3.96 3.92 3.90 3.87 6 7 5.59 4.74 4.35 4.12 3.97 3.87 3.79 3.73 3.68 3.64 3.57 3.53 3.49 3.47 3.44 7 8 5.32 4.46 4.07 3.84 3.69 3.58 3.50 3.44 3.39 3.35 3.28 3.24 3.20 3.17 3.15 8 9 5.12 4.26 3.86 3.63 3.48 3.37 3.29 3.23 3.18 3.14 3.07 3.03 2.99
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