- ￥431 - 5200
- MedChemExpress(MCE)
- 美国
- HY-15655
- 2025年12月05日
企业认证
相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 技术资料
- 保存条件：
Powder: -20°C, 3 years; 4°C, 2 years.In solvent: -80°C, 6 months; -20°C, 1 month.
- 库存：
货期：1-2天
- 供应商：
MedChemExpress LLC
- CAS号：
196808-24-9
- 规格：
10 mM * 1 mL/1 mg/5 mg/10 mg/25 mg/50 mg
| 规格： | 10 mM * 1 mL | 产品价格： | ￥1045.0 |
|---|---|---|---|
| 规格： | 1 mg | 产品价格： | ￥431.0 |
| 规格： | 5 mg | 产品价格： | ￥950.0 |
| 规格： | 10 mg | 产品价格： | ￥1650.0 |
| 规格： | 25 mg | 产品价格： | ￥3550.0 |
| 规格： | 50 mg | 产品价格： | ￥5200.0 |
MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务。
GW1929
CAS No. : 196808-24-9
MCE 国际站：GW1929
产品活性：GW1929 是有效的、具有口服活性的 PPAR-γ 激动剂，对人 PPAR-γ 的 pKi 为8.84。对人和鼠的 pEC50 分别为8.56 和 8.27。GW 1929 (hydrochloride) 具有抗糖尿病效果和神经保护作用。
研究领域：Cell Cycle/DNA Damage | Vitamin D Related/Nuclear Receptor
作用靶点：PPAR
In Vitro: GW1929 is a potent PPAR-γ activator, with pKis of 8.84, < 5.5, and < 6.5 for human PPAR-γ, PPAR-α, and PPAR-δ, and pEC50s of 8.56 and 8.27 for human PPAR-γ and murine PPAR-γ, respectively.
GW1929 (10 μM) inhibits TBBPA-induced caspase-3 increase and TBBPA-stimulated LDH release in neocortical cell cultures.
In Vivo: GW1929 (0.5, 1, 5 mg/kg, p.o.) highly decreases nonfasted plasma glucose levels in Zucker diabetic fatty (ZDF) rats after treatment for 14 days, and possesses antilipolytic efficacy. GW1929 (1, 5 mg/kg, p.o.) increases glucose-stimulated insuline secretion of β-cell in ZDF rats.
相关产品：Bioactive Compound Library Plus | Cell Cycle/DNA Damage Compound Library | Peptidomimetic Library | Anti-Aging Compound Library | Anti-diabetic Compound Library | Orally Active Compound Library | Neuroprotective Compound Library | Anti-Obesity Compound Library | Transcription Factor-Targeted Library | Lipid Metabolism Compound Library | Targeted Diversity Library | Antidepressant Compound Library | Nuclear Receptor Compound Library | Osteogenesis Compound Library | Cancer Stem Cells Compound Library | Heterocyclic Compound Library | Mitochondrial Protection Compound Library | Highly Selective Activators Library | Retinoic acid | Rosiglitazone | GW9662 | Pioglitazone | Fenofibrate | GW6471 | Fisetin | T0070907 | Pirinixic acid | 5-Aminosalicylic Acid | Troglitazone | GW 501516 | Daidzein | Icariin | Astaxanthin | Lanifibranor | GW7647 | Bezafibrate | Gemfibrozil 1-O-β-glucuronide | Elafibranor | MK-886 | GSK0660 | GW0742 | Glabridin | GSK3787 | FH535 | Magnolol | Candesartan | Gemfibrozil
热门产品线：重组蛋白 | 化合物库 | 天然产物 | 荧光染料 | PROTAC | 同位素标记物
Trending products：Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Dye Reagents | PROTAC | Isotope-Labeled Compounds
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
技术资料暂无技术资料 索取技术资料
