CDD0102,146422-58-4

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CDD0102

CAS No. : 146422-58-4

MCE 国际站：CDD0102

产品活性：CDD0102 是一种有效的 M₁ 毒蕈碱 (Muscarinic) 受体激动剂。

研究领域：GPCR/G Protein  |  Neuronal Signaling

作用靶点：mAChR

In Vitro: CDD0102 (CDD-0102) is an efficacious muscarinic agonist in cell lines expressing M₁ receptors. CDD0102 displays much lower activity at M₃ and M₅ receptors.

In Vivo: After i.p. injections, CDD0102 (CDD-0102) crosses the blood-brain barrier (BBB) in a dose-dependent manner. In toxicological studies, the LD₅₀ of CDD0102 is 190 mg/kg following i.p. injections and greater than 1,000 mg/kg following oral administration. In follow-up studies, after oral administration at a dose of 10 mg/kg, CDD0102 fully reverses memory deficits associated with IgG-192 saporin administration. Again, no side effects are observed at this dose.

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