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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
Powder: -20°C, 3 years; 4°C, 2 years.In solvent: -80°C, 6 months; -20°C, 1 month.
- 英文名:
CID-7345532
- 库存:
货期:1-2天
- 供应商:
MedChemExpress LLC
- CAS号:
878978-76-8
- 规格:
10 mM * 1 mL/1 mg/5 mg/10 mg/25 mg
| 规格: | 10 mM * 1 mL | 产品价格: | ¥770.0 |
|---|---|---|---|
| 规格: | 1 mg | 产品价格: | ¥350.0 |
| 规格: | 5 mg | 产品价格: | ¥700.0 |
| 规格: | 10 mg | 产品价格: | ¥1200.0 |
| 规格: | 25 mg | 产品价格: | ¥2550.0 |
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ML-098
CAS No. : 878978-76-8
MCE 国际站:ML-098
产品活性:ML-098(CID-7345532)是GTP结合蛋白Rab7的激活剂,EC50值为77.6nM。
研究领域:GPCR/G Protein
作用靶点:Ras
In Vitro: Probe compound mL098 (CID-7345532) functions by increasing the affinity of the GTPases for guanine nucleotides, leading to the hypothesis that these activators interact with GTPases bind to an allosteric binding site localized between switch regions I and II. ML-098 is an activator of the GTP-binding protein Rab7 with an EC50 of 77.6 nM which shows selectivity against the related GTPases cdc42, Ras, Rab-2A, and Rac1 (EC50s = 588.8, 346.7, 158.5, and 794.3 nM, respectively).
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文献和实验PREPARATION OF STOCK SOLUTIONS FOR FISH
buffer pH7.0 -for 100 ml prepare separate 100 ml of 6.8045 g KH2PO4 (1) 100 ml of 7.098 g Na2HPO4(2) -take 77 ml of solution (2) and mix with 33 ml of solution (1) 20xSSC -dissolve 175.3 g NaCl and 88.23 g tri-sodium-citrate in 900 ml of water
1、 水化上样缓冲液( I ) : 尿素 8M 4.805g CHAPS 4% 0.4g DTT 65mM 0.098g (现加) Bio-Lyte 0.2%(w/v) 50 m l ( 40% )(现加) 溴酚蓝 0.001% 10 m l ( 1% 溴酚蓝) MilliQ 水 定容至 10ml 分装成 10 小管,每小管 1ml , -20 ℃冰箱保存。 2、水化上样缓冲液( II ): 尿素 7M 4.2g 硫脲 2M 1.52g CHAPS 4% 0.4g
CsCl - density separation of DNA
and cuvettes Procedure 1.Determine the G C content of the sample DNA (Exercise 14.5) 2.Once the G C content is determined, the bouyant density of the DNA can be determined from the formula: p = 1.660 g/cm 3 0.098 x (G C fraction) Using the bouyant
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