Betamethasone盐酸倍他米松,956901-32-

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Betamethasone hydrochloride

CAS No. : 956901-32-9

MCE 国际站：Betamethasone hydrochloride

产品活性：Betamethasone hydrochloride 是一种合成糖皮质激素，具有抗炎和免疫抑制活性。Betamethasone hydrochloride 可加速胎儿肺成熟并诱导基因表达和细胞凋亡。

研究领域：Immunology/Inflammation  |  Vitamin D Related/Nuclear Receptor  |  Apoptosis

作用靶点：Glucocorticoid Receptor  |  Apoptosis

In Vitro: Betamethasone (0.1-1 μM; 12 h) induces gene expression in L929 cells.
Betamethasone (0.1-1 μM; 48 h) induces CEM C7 T-cells apoptosis.

In Vivo: Betamethasone (0.48 mg; i.v.gtt for 48 h) decreases the hypercapnia-induced increase in CBF due to decreased cerebral vasodilatation.Betamethasone (0.05 ml (1 mg/L); topical injection) ameliorates spinal nerve transection induced mechanical allodynia and thermal hyperalgesia, and reduces the activation of NF-κB and elevation of TNFα and IL-1β, and induces the expression of IL-10 in the rats brain.

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