- ￥400 - 4500
- MedChemExpress(MCE)
- 美国
- HY-16782
- 2025年12月05日
企业认证
相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 技术资料
- 保存条件：
Powder: -20°C, 3 years.In solvent: -80°C, 6 months; -20°C, 1 month.
- 英文名：
ARRY-614
- 库存：
货期：1-2天
- 供应商：
MedChemExpress LLC
- 规格：
10 mM * 1 mL/1 mg/5 mg/10 mg/25 mg/50 mg
| 规格： | 10 mM * 1 mL | 产品价格： | ￥1163.0 |
|---|---|---|---|
| 规格： | 1 mg | 产品价格： | ￥400.0 |
| 规格： | 5 mg | 产品价格： | ￥950.0 |
| 规格： | 10 mg | 产品价格： | ￥1500.0 |
| 规格： | 25 mg | 产品价格： | ￥3200.0 |
| 规格： | 50 mg | 产品价格： | ￥4500.0 |
MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务。
Pexmetinib
CAS No. : 945614-12-0
MCE 国际站：Pexmetinib
产品活性：Pexmetinib 是一种有效的 Tie-2 和 p38 MAPK 双重抑制剂，对 Tie-2，p38α 和 p38β 的 IC50 值分别为 1 nM，35 nM 和 26 nM，可用于急性骨髓性白血病的研究。
研究领域：MAPK/ERK Pathway | Autophagy
作用靶点：p38 MAPK | Autophagy
In Vitro: Pexmetinib is a Tie-2 and p38 MAPK dual inhibitor, with IC50s of 1 nM, 35 nM and 26 nM for Tie-2, p38α and p38β, respectively. Pexmetinib also shows IC50s of 4 nM (Abl), 10 nM (Arg), 28 nM (FGFR1), 47 nM (Flt1), 42 nM (Flt4), 41 nM (Fyn), 26 nM (Hck), 25 nM (Lyn), and 26 nM (MINK), respectively. Pexmetinib (0.5, 1 μM) blocks leukemic cell proliferation and stimulates hematopoietic activity in myelodysplastic syndromes.
相关产品：Drug Repurposing Compound Library Plus | Clinical Compound Library Plus | Bioactive Compound Library Plus | Immunology/Inflammation Compound Library | Kinase Inhibitor Library | MAPK Compound Library | Protein Tyrosine Kinase Compound Library | Anti-Cancer Compound Library | Clinical Compound Library | Autophagy Compound Library | Drug Repurposing Compound Library | Reprogramming Compound Library | Oxygen Sensing Compound Library | Pyroptosis Compound Library | Anti-Lung Cancer Compound Library | Anti-Blood Cancer Compound Library | Anti-Cancer Metabolism Compound Library | Neurodegenerative Disease-related Compound Library | Anti-Obesity Compound Library | Angiogenesis-Related Compound Library | Antidepressant Compound Library | Human Metabolite Library | Anti-Prostate Cancer Compound Library | Anti-Pulmonary Fibrosis Compound Library | Heterocyclic Compound Library | Pain-Related Compound Library | Membrane Protein-targeted Compound Library | Cell Death Library | Serine/Threonine Kinase Inhibitor Library | Adezmapimod | SB 202190 | Afatinib | Doramapimod | Aspirin | Oxidopamine hydrobromide | BI-3406 | Butyzamide | Hesperetin | Muramyl dipeptide | C16-PAF | Ralimetinib dimesylate | PD 169316 | Dehydrocorydaline | LXH254 | Neflamapimod | Diprovocim | Losmapimod | PF-3644022 | Exarafenib | Semapimod tetrahydrochloride | Talmapimod | PH-797804 | Sotorasib racemate | MAPK13-IN-1 | SB 239063 | VX-702
热门产品线：重组蛋白 | 化合物库 | 天然产物 | 荧光染料 | PROTAC | 同位素标记物
Trending products：Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Dye Reagents | PROTAC | Isotope-Labeled Compounds
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
技术资料暂无技术资料 索取技术资料
