SJFα,2254609-27-1

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SJFα

CAS No. : 2254609-27-1

MCE 国际站：SJFα

产品活性：SJFα 是一种 13 个原子长度 linker 的基于von Hippel-Lindau 配体的 PROTAC。SJFα 降解 p38α，DC₅₀ 为 7.16 nM，但降解 p38δ 效果较差 (DC₅₀=299 nM)，且在浓度高达 2.5 μM 时也不会降解其他 p38 亚型 (β 和 γ)。

研究领域：PROTAC  |  MAPK/ERK Pathway  |  Autophagy

作用靶点：PROTACs  |  p38 MAPK  |  Autophagy

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