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- 2025年12月05日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
Powder: -20°C, 3 years; 4°C, 2 years.In solvent: -80°C, 6 months; -20°C, 1 month.
- 库存：
货期：1-2天
- 供应商：
MedChemExpress LLC
- CAS号：
135330-08-4
- 规格：
10 mM * 1 mL/1 mg/5 mg/10 mg/25 mg
| 规格： | 10 mM * 1 mL | 产品价格： | ￥3391.0 |
|---|---|---|---|
| 规格： | 1 mg | 产品价格： | ￥1035.0 |
| 规格： | 5 mg | 产品价格： | ￥1600.0 |
| 规格： | 10 mg | 产品价格： | ￥2560.0 |
| 规格： | 25 mg | 产品价格： | ￥4640.0 |
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RP-54745
CAS No. : 135330-08-4
MCE 国际站：RP-54745
产品活性：RP-54745 是一种潜在的治风湿化合物，能够抑制噬细胞刺激和的白介素-1 (interleukin-1) 的产生。
作用靶点：Interleukin Related
In Vitro: RP-54745 diminishes LPS-induced interleukin-1 (IL-1) production by murine peritoneal macrophages.
In Vivo: RP-54745 (5 mg/kg) is effective at moderating oral doses in different mouse models of induced arthritis and in the MRL/lpr mice, genetically predisposed to develop an autoimmune pathology including arthritic disorders. The clinical status of the MRL mice, and several of their disturbed biochemical and immunological parameters, improved after a 3-month treatment with RP-54745.
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文献和实验|51475426|ref|XM_496493.1| PREDICTED: Homo sapiens simila... 38 0.69 gi|34740425|gb|AC122299.5| Mus musculus BAC clone RP23-270L... 36 2.7 gi|38229493|gb|AC133210.3| Mus musculus chromosome UNK clon... 36 2.7 gi|38142554|gb|AC114987.10| Mus musculus
方法）以及振动试验法（振动法）。 （1）ASTM-F-51法（显微镜法） 测试探头装有过滤隔膜，直接连接吸风计量泵，通过的空气量为28L/min。测试时使空气通过试验衣料，将空气中含有的发尘粒子捕到试验用的滤膜上，用400倍显微镜观察并统计尘埃粒子数。 读出滤膜上面的0.5-5以及5以上的粒子个数。在滤膜上面印有3.08mm的格子，可以读出一个格子内的粒子数。 （2）ASTM-F-51修订法（计数法） 使空气通过试验衣料，用粒子计数器测定发尘粒子的大小和个数。 把试样放置在带金属网的台
were significantly decreased. High expressions of Bcl-2 and Bax were detected in 1 and 2μmol/L arseni c trioxide-treated cells, these were 46%, 87.33% and 83.08%, 95.83% respecti vely, among which that of Bax was more significant. Arsenic trioxide treatment at 0.5μ
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