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ZM223
CAS No. : 2031177-48-5
MCE 国际站：ZM223
产品活性：ZM223 是一种有效的非共价 NEDD8 活化酶 (NAE) 抑制剂，具有口服活性。
研究领域：Metabolic Enzyme/Protease
作用靶点：NEDD8-activating Enzyme
In Vitro: ZM223 (0.1-1 μM; 4 hours) inhibits both HCT-116 and U-2OS cancer cells with IC50s of 100 and 122 nM, respectively.
ZM223 (0.1-1 μM; 4 hours) causes a dose-response decrease in the level of NEDD8 and accumulation of the UBC12 protein, indicating the decrease of the subsequent NEDD8-UBC12 complex.
相关产品：Pevonedistat | TAS4464 | NAcM-OPT | ZM223 hydrochloride
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Polyclonal IL-2 88-7824 JES6-1A12 JES6-5H4 IL-4 88-7844 11B11 BVD6-24G2 IL-5 88-7825 TRFK5 TRFK4
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