- ￥863 - 3500
- MedChemExpress(MCE)
- 美国
- HY-117244
- 2025年07月10日
企业认证
相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
Powder: -20°C, 3 years; 4°C, 2 years. In solvent: -80°C, 6 months; -20°C, 1 month.
- 库存：
货期：1-2天
- 供应商：
MedChemExpress LLC
- 规格：
10 mM * 1 mL/1 mg/5 mg/10 mg
| 规格： | 10 mM * 1 mL | 产品价格： | ￥2090.0 |
|---|---|---|---|
| 规格： | 1 mg | 产品价格： | ￥863.0 |
| 规格： | 5 mg | 产品价格： | ￥1900.0 |
| 规格： | 10 mg | 产品价格： | ￥3500.0 |
MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务。
AZD7507
CAS No. : 1041852-85-0
MCE 国际站：AZD7507
产品活性：AZD7507 为一种有效的、可口服的 CSF-1R 抑制剂，具有抗肿瘤活性。
研究领域：Protein Tyrosine Kinase/RTK
作用靶点：c-Fms
In Vitro: AZD7507 (Compound 31) inhibits the proliferation of 3T3 cells engineered to express CSF-1R and stimulated with CSF-1 (IC50, 32 nM), shows inhibitory activity against hERG and NaV1.5, with IC50s of >30 and 26 μM.
In Vivo: AZD7507 has good rat oral PK, with in vivo clearance of 7 mL/min/kg and 42% bioavailability. In the canine L-type Ca channel assay, the IC50 is >20 μM. AZD7507 significantly decreases the number of CD68+ macrophages in mice, and also reduces the volume and mass in mice bearing CC-LP-1 and SNU-1079 cells, but not WITT-1 cells.
相关产品：Bioactive Compound Library Plus | Kinase Inhibitor Library | Protein Tyrosine Kinase Compound Library | Anti-Cancer Compound Library | Orally Active Compound Library | Membrane Protein-targeted Compound Library | Cytokine Inhibitors Library | Pexidartinib | PLX5622 | Sotuletinib | Linifanib | Dovitinib | GW2580 | PLX5622 in AIN-76A Diet (1200 ppm) | Pazopanib Hydrochloride | Edicotinib | Vimseltinib | Chiauranib | PLX647 | Elzovantinib | Seralutinib | Emactuzumab | PRN1371 | c-Fms-IN-1 | Ki20227 | BPR1R024 | CSF1R-IN-1 | OSI-930 | Mavrilimumab | cFMS Receptor Inhibitor II | CSF1R-IN-3 | c-Fms-IN-10 | c-Fms-IN-13 | c-Fms-IN-8
热门产品线：重组蛋白 | 化合物库 | 天然产物 | 荧光染料 | PROTAC | 同位素标记物
Trending products：Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Dye Reagents | PROTAC | Isotope-Labeled Compounds
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验！ zhibinx2007 现在比较常用的有两种，可以用AZD235或BEZ8055。 寂寞小美鱼 目前有应用于临床的靶向药物吗？ selleckchem01 可以用于小胶质细胞的有：MK-2206；AT7867；CCT128930； 已经用于临床试验的有MK-2206 现给大家介绍一下主要的AKT抑制剂： MK-2206：a highly selective, potent
为什么你的 qPCR 重复性差？灵敏度低？扩增易受抑制？那是你还不知道数字 PCR
for copy number analysis of the CCL4L genes." Infection, Genetics and Evolution 25 (2014): 28 - 35.4.Oxnard, Geoffrey R., et al. "Association between plasma genotyping and outcomes of treatment with osimertinib (AZD9291) in advanced non–small-cell lung
Characterization of the Picrotoxin Site of GABAA Receptors
. 2012. AZD‐3043: A novel, metabolically labile sedative‐hypnotic agent with rapid and predictable emergence from hypnosis. Anesthesiology 116:1267‐1277. Elliott, K.A.C
技术资料暂无技术资料 索取技术资料
