SANT-1,304909-07-7

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SANT-1

CAS No. : 304909-07-7

MCE 国际站：SANT-1

产品活性：SANT-1 是一种有效的 Smo 拮抗剂，能够抑制 Hedgehog 通路，在 Shh-LIGHT2 和 SmoA1-LIGHT2 实验中，IC₅₀ 值分别为 20 nM 和 30 nM。

研究领域：Stem Cell/Wnt

作用靶点：Smo  |  Hedgehog

In Vitro: SANT-1 is a potent Smo antagonist, binds directly to Smo, and inhibits Hedgehog signaling, with IC₅₀s of 20 nM and 30 nM in Shh-LIGHT2 and SmoA1-LIGHT2 cells, respectively.
SANT-1 (1 μM, for 24 or 48 hours) decreases the proliferation of medulloblastoma cells.

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