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- 2025年12月05日
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PKG1α activator 3
CAS No. : 2773367-58-9
MCE 国际站：PKG1α activator 3
产品活性：PKG1α activator 3 是 PKG1α 激活剂 (EC50 basal/partial=13/0.52 μM)。PKG1α activator 3 对平滑肌细胞有抗增殖作用，可用于心血管疾病的研究。
研究领域：Others
作用靶点：Others
In Vitro: PKG1α activator 3 (11.7-33.3 μM; 45 min) shows phosphorylation of VASP.
PKG1α activator 3 (6.2-22.8 μM; 24 h) inhibits PDGF-induced cell proliferation.
In Vivo: PKG1α activator 3 shows acceptable in vivo rat pharmacokinetic profiles.
| pharmacokinetic parameters | ||||
| Compound | Cl (mL/min/kg) | Vd (L/kg) | MRT (h) | PPB (%) |
| PKG1α activator 3 | 8.1 | 0.45 | 0.9 | >99.9 |
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