- ￥700 - 4500
- MedChemExpress(MCE)
- 美国
- HY-112777
- 2025年12月05日
企业认证
相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 技术资料
- 保存条件：
Powder: -20°C, 3 years; 4°C, 2 years.In solvent: -80°C, 6 months; -20°C, 1 month.
- 库存：
货期：1-2天
- 供应商：
MedChemExpress LLC
- CAS号：
363571-83-9
- 规格：
10 mM * 1 mL/5 mg/10 mg/50 mg
| 规格： | 10 mM * 1 mL | 产品价格： | ￥830.0 |
|---|---|---|---|
| 规格： | 5 mg | 产品价格： | ￥700.0 |
| 规格： | 10 mg | 产品价格： | ￥1100.0 |
| 规格： | 50 mg | 产品价格： | ￥4500.0 |
MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务。
Kinesore
CAS No. : 363571-83-9
MCE 国际站：Kinesore
产品活性：Kinesore 是 KLC2-SKIP 相互作用的抑制剂。
研究领域：Others
作用靶点：Others
In Vitro: Remarkably, in kinesore-treated cells, the microtubule network is entirely reorganized into a series of loops and bundles. In addition, the lysosomal compartment accumulates in a juxtanuclear position, where there are relatively few microtubules. At 50 μM kinesore, this phenotype is highly penetrant, with 95±2.4% (n=3, total of 200 cells) of cells exhibiting a reorganized nonradial microtubule network. In titration experiments, in cells treated for 1 h, this phenotype becomes apparent at a concentration of 25 μM kinesore, with relatively little effect at or below concentrations of 12.5 μM. The effect is reversible because a 2-h washout of kinesore from cells treated for 1 h led to the reestablishment of the radial microtubule array. This kinesore-induced reorganization of the microtubule network is observed in a panel of mammalian normal and cancer cell lines. In wild-type cells, 50 μM kinesore induces the remodeling of the microtubule network and the formation of extensive microtubule-rich projections. This phenotype is strongly suppressed in Kif5B knockout cells, confirming that microtubule remodeling induced by kinesore is dependent upon the presence of kinesin-1.
相关产品：Bioactive Compound Library Plus | Peptidomimetic Library | Targeted Diversity Library | Digitonin | 5-Ph-IAA | FLAG peptide | Tocofersolan | Monocrotaline | Lactate sodium | TCEP hydrochloride | 3X FLAG peptide | DPPH | Pertussis Toxin | Pronase E (Activity ≥ 7000 U/g) | O-Propargyl-Puromycin | NMDI14 | Phytohemagglutinin | MYLS22 | Hyaluronidase | Biotinyl tyramide | Kifunensine | Human IgG1 kappa, Isotype Control | 4-Azido-L-phenylalanine | 6-Aminonicotinamide | Ammonium tetrathiomolybdate(VI) | OVA Peptide(257-264) TFA | Alkyne-phenol | Lauryl maltose neopentyl glycol | SHIN1 | CHAPS | Cytosporone B
热门产品线：重组蛋白 | 化合物库 | 天然产物 | 荧光染料 | PROTAC | 同位素标记物
Trending products：Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Dye Reagents | PROTAC | Isotope-Labeled Compounds
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
技术资料暂无技术资料 索取技术资料
