MCE 的所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务。
MCE 国际站:Lipid GPCR Library
A unique collection of 5,440 small molecules targeting the family of eight endothelial differentiation gene (EDG) receptors (S1P1–5 and LPA1–3) which is suitable for Lipid GPCR screening research.
Description & Advantages:
• A set of 5,440 compounds targeting lipid GPCR.
• The collection may also be appropriate for screening at GPR3, GPR6 and GPR12 orphan receptors given some TM bundle binding site similarity and/or GPR23, GPR92 and P2Y5 given their more recent classification as additional, albeit distinct, LPA receptors.
• The compounds have been selected using a combination of ligand-based methods using chemical fingerprints, 2D pharmacophores and 3D shape/feature matches.
• Structurally diverse.
• NMR and HPLC validated to ensure high purity and quality.
• All compounds can be readily followed with analogues either from stock or from new synthesis.
• Databases and compounds are provided by Enamine.