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MCE 国际站:FDA-Approved Drug Library Mini
New drug development is a time-consuming and high-cost process. Drug repurposing (also called drug repositioning, reprofiling or re‑tasking) offers various advantages over developing an entirely new drug for a given indication. First, the risk of failure is lower. Second, the time frame for drug development can be reduced. Third, less investment is needed. Approved drugs have identified bioactivities, good pharmacokinetic characteristics and safety which are suitable for drug repurposing. MCE owns a unique collection of 2801 approved compounds which have been completed extensive preclinical and clinical studies and have well-characterized bioactivities, safety and bioavailability properties. The package of this library is 96-well microplate with peelable foil seal, which makes the screening process easier and faster.
Description & Advantages:
• A unique collection of 2801 approved drugs for high throughput screening (HTS) and high content screening (HCS).
• Used in the research of oncology, cardiology, anti-inflammatory, immunology, dermatology, endocrinology, neurology, and more.
• A useful tool for researching new targets of marketed old drugs.
• All compounds have been approved by the FDA, EMA and other countries.
• Structurally diverse, bioactive, and cell permeable.
• More detailed compound information with structure, IC50, and brief introduction.
• NMR and HPLC validated ensure high purity.
• All compounds are in stock and continuously updated.
• Easily peelable foil seal makes the screening process easier and faster.
• Lower price, more compounds.
• Avoid multiple and uneven dispensing.
• Reduce risks of product cross-contamination.
• Avoid reduced activity due to long-term storage.
FAQ
1 Can we centrifuge the whole rack?
Yes. It is advised to centrifuge all of the samples before experimental use. Recommended centrifugation for this plate is 1000g or less.
2 How can I use the 2D barcode on the microplate lid?
Use an HD barcode scanner to scan the barcode, and then find the corresponding plate and compound information in the Excel or the provided hard copy.
3 What are the appropriate compound storage conditions?
For solutions, store at -80°C. For some special compounds, specific handling instructions are provided.
4 After receiving the compound library, the ice box has melted, will this affect the efficacy of thecompound?
MCE products are primarily chemical synthesis products which are not temperature sensitive. The ice boxes inside of the packages are used to prevent the occurrence of extreme temperatures during the process of transportation, and a melted icebox will not affect the reagent quality. After transit, the icebox is no longer needed.