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- MedChemExpress(MCE)
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- 2025年12月05日
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DNA Library
MCE 国际站：DNA Library
A unique collection of 5,530 compounds designed for identification of new actives against proteins essential for DNA stability. The library comprises compounds with in silico predicted activity against key housekeeping proteins essential for DNA stability.
Description & Advantages:
• A unique collection of 5,530 compounds designed for identification of new actives against proteins essential for DNA stability.
• No PAINS (Pan Assay Interference Compounds), only medchem friendly compounds.
• Structurally diverse.
• NMR and HPLC validated to ensure high purity and quality.
• All compounds can be readily followed with analogues either from stock or from new syntheses.
• Databases and compounds are provided by Enamine.
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文献和实验Shotgun Library Construction for DNA Sequencing
Shotgun cloning is a method to generate the templates needed for DNA sequencing. This process entails breaking a large target DNA randomly into smaller fragments; end sequencing these smaller fragments; and from the overlapping sequences
OGMP - Organelle DNA Library Construction
Acetate (Sorvall), wash, dry at 65'C to remove NH4+. Use 0.5 - 2 ug PER LIBRARY (for 30 - 100 kbp genome size) II. END REPAIR ~1.0 ug fragmented DNA 1.5 ul dNTP-mix (stock: 1 mM each1)) 2 units Klenow
Native Chromatin Preparation and Illumina/Solexa Library Construction
DNA Repair and Solexa Library Construction 39. Repair DNA ends to generate blunt-ended DNA using the DNA End-Repair Kit (Epicentre). Combine: 1-34 µL of DNA (0.3 µg) 5 µL of 10X End-Repair
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