Biosimilar Antibodies for Rese

Biosimilar Antibodies for Research Use，研究用生物仿制药抗体（科学研究用）（仅限科学研究，不得用于临床及其人体治疗。）
链接：https://www.bio-rad-antibodies.com/biosimilar-monoclonal-antibodies-research-use.html

Table 1. Biosimilar research antibodies

Biotherapeutic Antibody	Antibody Specificity	Bio-Rad Biosimilar (Cat. #)	Supporting Anti-Drug Antibodies
Adalimumab	Human Anti-TNF alpha Antibody	MCA6088	Anti-Adalimumab Antibodies
Alemtuzumab	Human Anti-CD52 Antibody	MCA6101	Anti-Alemtuzumab Antibodies
Bevacizumab	Human Anti-VEGF Antibody	MCA6089	Anti-Bevacizumab Antibodies
Cetuximab	Human Anti-EGFR Antibody	MCA6102	Anti-Cetuximab Antibodies
Eculizumab	Human Anti-C5 Antibody	MCA6103	Anti-Eculizumab Antibodies - Coming soon
Infliximab	Human Anti-TNF alpha Antibody	MCA6090	Anti-Infliximab Antibodies
Natalizumab	Anti-Integrin Alpha 4 Antibody	MCA6104	Anti-Natalizumab Antibodies
Omalizumab	Human Anti-IgE Antibody	MCA6105	Anti-Omalizumab Antibodies
Rituximab	Human Anti-CD20 Antibody	MCA6091	Anti-Rituximab Antibodies
Tocilizumab	Human Anti-IL6R Antibody	MCA6106	Anti-Tocilizumab Antibodies
Trastuzumab	Human Anti-ErbB2 Antibody	MCA6092	Anti-Trastuzumab Antibodies

Each biosimilar research antibody has been produced using a recombinant platform and incorporates the publicly available sequence of the variable region (specificity) of the original monoclonal antibody drug. These biosimilar products are supplied in a research grade format, i.e. in PBS buffer with preservative; they are not manufactured or formulated in the same way as the therapeutic reference product. A comparison of these antibodies with their respective therapeutic reference products was carried out to show biosimilarity, Figures 1 and 2.

Purity and Monodispersity

All of our biosimilar research antibodies show comparable purity and monodispersity with the reference product. Purity was measured by band quantification of a Coomassie stained SDS-PAGE gel; monodispersity was compared using size exclusion chromatography (SEC). Example data for Anti-TNF alpha Antibody and adalimumab are shown in Figure 1. Detailed comparison data for each antibody with its reference product is available on the respective product information page accessed via the link in Table 1.