- ￥1350 - 3000
- Proteintech
- 24173-1-AP
- 2025年10月13日
- IHC, ELISA
- Rabbit
- human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Recombinant human IL-1F6 protein
- 亚型：
IgG
- 保存条件：
Store at -20°C. Stable for one year after shipment.
- 克隆性：
Polyclonal
- 标记物：
Unconjugated
- 适应物种：
human
- 保质期：
详见产品包装
- 库存：
充足
- 宿主：
Rabbit
- 应用范围：
IHC, ELISA
- 靶点：
IL-1F6/IL-36 alpha
- 抗体英文名：
IL-1F6/IL-36 alpha Polyclonal antibody
- 抗体名：
IL-1F6/IL-36 alpha Polyclonal antibody
- 规格：
50ul/100ul/150ul
| 规格： | 50ul | 产品价格： | ￥1350.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥2200.0 |
| 规格： | 150ul | 产品价格： | ￥3000.0 |
经过测试的应用
| Positive IHC detected in | human tonsillitis tissue, human gliomas tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Immunohistochemistry (IHC) | IHC : 1:50-1:500 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
24173-1-AP targets IL-1F6/IL-36 alpha in IHC, ELISA applications and shows reactivity with human samples.
| 经测试应用 | IHC, ELISA |
| 文献引用应用 | IHC |
| 经测试反应性 | human |
| 文献引用反应性 | human |
| 免疫原 |
CatNo: Ag21487 Product name: Recombinant human IL-1F6 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 1-158 aa of BC107043 Sequence: MEKALKIDTPQQGSIQDINHRVWVLQDQTLIAVPRKDRMSPVTIALISCRHVETLEKDRGNPIYLGLNGLNLCLMCAKVGDQPTLQLKEKDIMDLYNQPEPVKSFLFYHSQSGRNSTFESVAFPGWFIAVSSEGGCPLILTQELGKANTTDFGLTMLF |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | interleukin 1 family, member 6 (epsilon) |
| 别名 | IL1F6, IL-36 Alpha, IL-36α, IL 1F6, IL-1F6 |
| 计算分子量 | 158 aa, 18 kDa |
| GenBank蛋白编号 | BC107043 |
| 基因名称 | IL-1F6/IL-36 alpha |
| Gene ID (NCBI) | 27179 |
| RRID | AB_2879446 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q9UHA7 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
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文献和实验| Species | Application | Title |
|---|---|---|
| human | IHC | J Cutan Pathol IL-36α and IL-36γ expressions in the differential diagnosis of palmoplantar psoriasis and palmoplantar eczema: A retrospective histopathologic and immunohistochemical study.Authors - Ozan Erdem |
| human | IHC | Exp Dermatol Clinical Responses and Transcriptomic Analysis of Spesolimab in a Girl With Severe Dermatitis, Multiple Allergies and Metabolic Wasting SyndromeAuthors - Jinxiang Yang |
IB Kinase and NF-B Signaling in Response to Pro-Inflammatory Cytokines
Exposure to pro-inflammatory cytokines (TNFα and IL-1) results in activation of signaling cascades that lead to stimulation of activity of the transcription factors AP-1 and NF-κB and induction of genes that are controlled
，间接推算出细胞因子的生物学活性单位。 一、IL-1生物学活性检测 白细胞介素-1（IL-1）主要是由活化的单核-巨噬细胞合成和分泌的一种细胞因子，具有活化淋巴细胞、协同刺激胸腺细胞增殖、参与抗体产生和促炎症反应等多种生物学功能。IL-1有IL-1α和IL-1β构成，结合同种受体，表现相同的生物学活性。用于检测IL-1生物活性的方法有多种，如小鼠胸腺细胞增殖法、D10G4.1细胞增殖法、EL-4细胞测定法等。
accumulation by LPS, as TLR4 can use either MyD88 or TRIF. The net result of these interactions was activation of the transcription factors NF-{kappa}B and AP-1, and synthesis of TNF-{alpha} mRNA. TNF-{alpha} acts through an apparent autocrine pathway
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