产品封面图
文献支持

ECM1 多克隆抗体 11521-1-AP

收藏
  • ￥1350 - 3000
  • Proteintech已认证
  • 11521-1-AP
  • 2025年10月13日
  • WB, IHC, IF/ICC, ELISA
  • Rabbit
  • human, mouse, rat
avatar
Proteintech中国公司
品牌商
18 年钻石会员

  • 企业认证

    点击 QQ 联系

    • 相关产品推荐更多 >

    万千商家帮你免费找货

    0 人在求购买到急需产品
    • 详细信息
    • 文献和实验
    • 技术资料
    • 免疫原：

      Recombinant human ECM1 protein

    • 亚型：

      IgG

    • 保存条件：

      Store at -20°C. Stable for one year after shipment.

    • 克隆性：

      Polyclonal

    • 标记物：

      Unconjugated

    • 适应物种：

      human, mouse, rat

    • 保质期：

      详见产品包装

    • 库存：

      充足

    • 宿主：

      Rabbit

    • 应用范围：

      WB, IHC, IF/ICC, ELISA

    • 靶点：

      ECM1

    • 抗体英文名：

      ECM1 Polyclonal antibody

    • 抗体名：

      ECM1 Polyclonal antibody

    • 规格：

      50ul/100ul/150ul

    规格：50ul产品价格：￥1350.0
    规格：100ul产品价格：￥2200.0
    规格：150ul产品价格：￥3000.0

    经过测试的应用

    Positive WB detected inA549 cells, L02 cells, HepG2 cells, mouse liver tissue, mouse kidney tissue, MCF-7 cells, mouse pancreas tissue, rat pancreas tissue, A375 cells
    Positive IHC detected inhuman thyroid cancer tissue, human breast cancer tissue, human lung cancer tissue, human pancreas cancer tissue
    Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
    Positive IF/ICC detected inHepG2 cells
    Planning an IHC experiment? We recommend our IHCeasy ECM1 Ready-To-Use IHC Kit. ECM1 primary antibody included.

    推荐稀释比

    应用推荐稀释比
    Western Blot (WB)WB : 1:500-1:2000
    Immunohistochemistry (IHC)IHC : 1:100-1:400
    Immunofluorescence (IF)/ICCIF/ICC : 1:50-1:500
    It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
    Sample-dependent, Check data in validation data gallery.

    产品信息

    11521-1-AP targets ECM1 in WB, IHC, IF/ICC, IP, ELISA applications and shows reactivity with human, mouse, rat samples.

    经测试应用 WB, IHC, IF/ICC, ELISA
    文献引用应用WB, IHC, IF, IP
    经测试反应性 human, mouse, rat
    文献引用反应性human, mouse, canine
    免疫原

    CatNo: Ag2084

    Product name: Recombinant human ECM1 protein

    Source: e coli.-derived, PGEX-4T

    Tag: GST

    Domain: 241-540 aa of BC023505

    Sequence: MSRFCEAEFSVKTRPHWCCTRQGEARFSCFQEEAPQPHYQLRACPSHQPDISSGLELPFPPGVPTLDNIKNICHLRRFRSVPRNLPATDPLQRELLALIQLEREFQRCCRQGNNHTCTWKAWEDTLDKYCDREYAVKTHHHLCCRHPPSPTRDECFARRAPYPNYDRDILTIDISRVTPNLMGHLCGNQRVLTKHKHIPGLIHNMTARCCDLPFPEQACCAEEEKLTFINDLCGPRRNIWRDPALCCYLSPGDEQVNCFNINYLRNVALVSGDTENAKGQGEQGSTGGTNISSTSEPKEE
    宿主/亚型 Rabbit / IgG
    抗体类别 Polyclonal
    产品类型 Antibody
    全称 extracellular matrix protein 1
    别名 Secretory component p85, extracellular matrix protein 1
    计算分子量 540 aa, 61 kDa
    观测分子量55-61 kDa
    GenBank蛋白编号BC023505
    基因名称 ECM1
    Gene ID (NCBI) 1893
    RRIDAB_2261964
    偶联类型 Unconjugated
    形式Liquid
    纯化方式Antigen affinity purification
    UNIPROT IDQ16610
    储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
    储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

    背景介绍

    Extracellular matrix protein 1 (ECM1) is a glycoprotein involved in a number of biological processes such as bone formation, skin differentiation, cell proliferation, and promotes angiostasis.ECM1 is expressed in breast cancer and could participate in cell migration and angiogenesis. Pathologically, ECM1 contributes to the formation and metastasis of several types of cancer including breast, thyroid and hepatocellular cancers.(PMID:21128013) It inhibits MMP9 proteolytic activity. ECM1 protein is a possible trigger for angiogenesis, tumor progression and malignancies(PMID:21497598).

    风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。

    图标文献和实验
    该产品被引用文献
    SpeciesApplicationTitle

    Dev Cell

    Spatial Control of Primary Ciliogenesis by Subdistal Appendages Alters Sensation-Associated Properties of Cilia.

    Authors - Gregory Mazo
    humanWB

    Cell Mol Life Sci

    Crip2 affects vascular development by fine-tuning endothelial cell aggregation and proliferation

    Authors - Shuaiqi Yang
    humanIF

    Oncogene

    Extracellular matrix protein 1 promotes cell metastasis and glucose metabolism by inducing integrin β4/FAK/SOX2/HIF-1α signaling pathway in gastric cancer.

    Authors - L Gan
    humanWB,IHC,IF

    J Biol Chem

    Phospholipid scramblase 1 is secreted by a lipid raft-dependent pathway and interacts with the extracellular matrix protein 1 in the dermal epidermal junction zone of human skin.

    Authors - Merregaert Joseph J
    humanWB,IHC

    Am J Transl Res

    miR-23a-5p inhibits cell proliferation and invasion in pancreatic ductal adenocarcinoma by suppressing ECM1 expression.

    Authors - Wenjie Huang
    humanIHC

    Food Chem Toxicol

    MiR-92a antagonized the facilitation effect of extracellular matrix protein 1 in GC metastasis through targeting its 3'UTR region.

    Authors - Lin-Qing Liu
    图标技术资料

    暂无技术资料 索取技术资料

    同类产品报价

    产品名称
    产品价格
    公司名称
    报价日期
    ECM1 多克隆抗体 30725-1-AP
    ￥1350
    Proteintech中国公司
    2025年10月09日询价
    ECM1 Rabbit pAb, AP conjugated(bs-24046R-AP)-100ul
    ￥2980
    北京博奥森生物技术有限公司
    2025年09月30日询价
    Ecm1 多克隆抗体 | Ecm1 polyclonal antibody
    询价
    艾美捷科技有限公司
    2025年07月08日询价
    ECM1 多克隆抗体
    ￥420
    武汉伊莱瑞特生物科技股份有限公司
    2025年07月13日询价
    ECM1 多克隆抗体
    询价
    武汉佰瑞得生物技术有限公司
    2025年07月12日询价
    文献支持
    ECM1 多克隆抗体 11521-1-AP
    ￥1350 - 3000