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- 详细信息
- 文献和实验
- 技术资料
- 库存:
239
- 英文名:
PDE1-IN-2
- CAS号:
1904611-63-7
- 保质期:
2年
- 供应商:
北京百奥莱博科技有限公司
- 保存条件:
-20℃
- 规格:
1mL(10mM)|1mg|5mg|10mg|50mg|100mg
特别提示:包括PDE1抑制剂(PDE1-IN-2)在内,本公司的所有产品仅可用于科研实验,严禁用于临床医疗及其他非科研用途!
产品名称:PDE1抑制剂(PDE1-IN-2)
英文名称:PDE1-IN-2
产品货号:M06386
产品规格:1mL(10mM)|1mg|5mg|10mg|50mg|100mg
PDE1-IN-2是PDE1的抑制剂,来自专利WO2016/55618A1,化合物实例31。对PDE1C,PDE1B和PDE1A的IC50值分别为6,140和164nM。
注:本品仅可用于科研实验,严禁用于临床医疗及其他用途!
CAS号:1904611-63-7
纯度:98.0%
分子式:C₁₆H₂₁BrN₄O₂
分子量:381.27
结构式:
储存条件:-20℃,有效期2年,溶入溶剂后-20℃请尽量在一个月内使用。
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文献和实验Radiolabeled Ligand Binding to the Catalytic or Allosteric Sites of PDE5 and PDE11
Cyclic nucleotide phosphodiesterases (PDEs) have been investigated for years as targets for therapeutic intervention in a number of pathophysiological processes. Phosphodiesterase-5 (PDE5), which is highly specific for guanosine 3′-5′-cyclic
Interactions Between Catalytic and Inhibitory Subunits of PDE6
Rod and cone photoreceptor guanosine 3′5′-cyclic-monophosphate phosphodiesterases (PDEs) are classified into the PDE6 family of cyclic nucleotide PDEs. A unique feature of the PDE6 enzymes is the presence of inhibitory γ-subunits (Pγ
Purification of PDE6 Isozymes From Mammalian Retina
The photoreceptor phosphodiesterase (PDE6) is the central effector of visual transduction in vertebrate retinal photoreceptors. Distinct isozymes of PDE6 exist in rods and cones. Mammalian retina serves as an abundant source of tissue for PDE
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